Ethyl N-cyclohexylcarbamate

Base Information

• Chemical Name: Ethyl N-cyclohexylcarbamate
• CAS No.: 1541-19-1
• Molecular Formula: C9H17 N O2
• Molecular Weight: 171.239
• Hs Code.: 2924299090
• NSC Number: 22457
• DSSTox Substance ID: DTXSID50165532
• Nikkaji Number: J245.897G
• Wikidata: Q83034756
• Mol file: 1541-19-1.mol

Synonyms:Ethyl N-cyclohexylcarbamate;Ethyl cyclohexanecarbamate;1541-19-1;N-Cyclohexaneurethane;Ethyl cyclohexylcarbamate;Ethyl N-cyclohexylurethane;Carbamic acid, cyclohexyl-, ethyl ester;N-Cicloesiluretanoetilico;Cyclohexanecarbamic acid ethyl ester;N-Cicloesiluretanoetilico [Italian];BRN 1908969;Carbamic acid,N-cyclohexyl-, ethyl ester;3-12-00-00047 (Beilstein Handbook Reference);cyclo-hexylurethan;Cyclohexanecarbamic acid, ethyl ester;SCHEMBL2802318;DTXSID50165532;NSC22457;NSC 22457;NSC-22457;AKOS003873343;LS-49209;Carbamic acid, N-cyclohexyl-, ethyl ester;FT-0765578

Chemical Property of Ethyl N-cyclohexylcarbamate

Chemical Property:

• Vapor Pressure: 0.00814mmHg at 25°C
• Boiling Point: 267.5°Cat760mmHg
• Flash Point: 115.6°C
• PSA: 38.33000
• Density: 1g/cm³
• LogP: 2.45610
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 171.125928785
• Heavy Atom Count: 12
• Complexity: 142

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)NC1CCCCC1

Technology Process of Ethyl N-cyclohexylcarbamate

There total 45 articles about Ethyl N-cyclohexylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

cyclohexane (110-82-7,25012-93-5) + N,O-bistrimethylsilyl-N-(ethoxycarbonyl)hydroxylamine (66121-61-7) → Hexamethyldisiloxane (107-46-0) + ethyl N-cyclohexylcarbamate (1541-19-1) + urethane (51-79-6)

Guidance literature:

at 100 ℃; for 25h;

DOI:10.1021/jo00315a024

Reference yield: 96.0%

1,3-Dicyclohexylurea (2387-23-7) → ethyl N-cyclohexylcarbamate (1541-19-1)

Guidance literature:

Reference yield: 96.0%

cyclohexylamine (108-91-8,157973-60-9) + ethyl iodide (75-03-6) + C10H16N2O2 (797761-95-6) → ethyl N-cyclohexylcarbamate (1541-19-1)

Guidance literature:

cyclohexylamine; C₁₀H₁₆N₂O₂; In acetonitrile; at 5 ℃; for 1.5h;

ethyl iodide; at 20 ℃; for 6h;

DOI:10.1016/S0040-4039(02)00697-4

upstream raw materials:

chloroformic acid ethyl ester

cyclohexylamine

ethanol

Cyclohexyl isocyanate

Downstream raw materials:

Chloromethyl-cyclohexyl-carbamic acid ethyl ester

3-cyclohexyl-5,6-diphenyl-[1,3]oxazine-2,4-dione

spiro[5.6]dodecan-7-one

cyclohexyl-(3-oxo-2,3-diphenyl-propionyl)-carbamic acid ethyl ester

Refernces

• 1、 Yoshimura,M. et al.. "-". . p. 2287 - 2288. Retrieved 1973.
• 2、 Abla,Choi,Sakakura. "Halogen-free process for the conversion of carbon dioxide to urethanes by homogeneous catalysis". . p. 2238 - 2239. Retrieved 2001.
• 3、 Lessard,J.,Paton,J.M.. "-". . p. 4883 - 4886. Retrieved 1970.
• 4、 Breslow,Edwards. "-". . p. 2123. Retrieved 1967.
• 5、 Saegusa et al.. "-". . p. 275. Retrieved 1970.
• 6、 Riemer, Daniel,Hirapara, Pradipbhai,Das, Shoubhik. "Chemoselective synthesis of carbamates using CO2 as carbon source". . p. 1916 - 1920. Retrieved 2018/08/17.