C₂₂H₁₈BrNO₂S

Base Information

• Chemical Name: C₂₂H₁₈BrNO₂S
• CAS No.: 1386384-18-4
• Molecular Formula: C₂₂H₁₈BrNO₂S
• Molecular Weight: 440.36
• Mol file: 1386384-18-4.mol

Synonyms:C₂₂H₁₈BrNO₂S

Chemical Property of C₂₂H₁₈BrNO₂S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₂₂H₁₈BrNO₂S

There total 3 articles about C₂₂H₁₈BrNO₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C22H16BrNO2S (1386384-17-3) → C22H18BrNO2S (1386384-18-4)

Guidance literature:

With palladium on activated charcoal; hydrogen; In ethyl acetate; at 20 ℃;

DOI:10.1021/ol301663h

Reference yield:

(2-bromobenzyl)triphenylphosphonium bromide (36901-75-4) → C22H18BrNO2S (1386384-18-4)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium tert-butylate / tetrahydrofuran / 20 °C / Inert atmosphere

2: palladium on activated charcoal; hydrogen / ethyl acetate / 20 °C

With palladium on activated charcoal; potassium tert-butylate; hydrogen; In tetrahydrofuran; ethyl acetate; 1: Wittig olefination;

DOI:10.1021/ol301663h

Reference yield:

1-(phenylsulfonyl)indole-3-carbaldehyde (80360-20-9) → C22H18BrNO2S (1386384-18-4)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium tert-butylate / tetrahydrofuran / 20 °C / Inert atmosphere

2: palladium on activated charcoal; hydrogen / ethyl acetate / 20 °C

With palladium on activated charcoal; potassium tert-butylate; hydrogen; In tetrahydrofuran; ethyl acetate; 1: Wittig olefination;

DOI:10.1021/ol301663h

upstream raw materials:

C₂₂H₁₆BrNO₂S

1-(phenylsulfonyl)indole-3-carbaldehyde

(2-bromobenzyl)triphenylphosphonium bromide

Downstream raw materials:

C₁₆H₁₄BrN

5,6-dihydro-11H-benzo[a]carbazole

C₁₆H₁₅N

Refernces