Tris(3-methoxyphenyl)phosphine

Base Information

• Chemical Name: Tris(3-methoxyphenyl)phosphine
• CAS No.: 29949-84-6
• Molecular Formula: C21H21O3P
• Molecular Weight: 352.37
• Hs Code.: 29310099
• European Community (EC) Number: 631-150-0
• NSC Number: 132543
• DSSTox Substance ID: DTXSID80184054
• Nikkaji Number: J1.092.463D
• Wikidata: Q72515240
• Mol file: 29949-84-6.mol

Synonyms:Tris(3-methoxyphenyl)phosphine;29949-84-6;tris(3-methoxyphenyl)phosphane;Phosphine, tris(3-methoxyphenyl)-;MFCD00008386;Tris(m-methoxyphenyl)phosphine;NSC132543;SCHEMBL197286;DTXSID80184054;Phosphine,tris(3-methoxyphenyl)-;CCXTYQMZVYIQRP-UHFFFAOYSA-N;AMY23385;BCP22505;AKOS007930493;CS-W014487;GC10065;NSC 132543;NSC-132543;AS-60114;SY042561;FT-0638890;T2946;A876344;J-525131;N-(2-CHLOROETHYL)-N-(4-METHYLCYCLOHEXYL)UREA;TRI(M-ANISYL)PHOSPHINE;TRIS(3-METHOXYPHENYL)PHOSPHANE;TRIS(3-METHOXYPHENYL)PHOSPHINE;TRIS(M-ANISYL)PHOSPHINE;TRIS(M-METHOXYPHENYL)PHOSPHINE

Chemical Property of Tris(3-methoxyphenyl)phosphine

Chemical Property:

• Appearance/Colour: White to almost white crystalline powder
• Vapor Pressure: 8.9E-09mmHg at 25°C
• Melting Point: 113-115 °C(lit.)
• Boiling Point: 476.3 °C at 760 mmHg
• Flash Point: 301.7 °C
• PSA: 41.28000
• LogP: 3.47060
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 352.12283153
• Heavy Atom Count: 25
• Complexity: 334

Purity/Quality:

99% ^*data from raw suppliers

tris(3-Methoxyphenyl)phosphine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=CC=C1)P(C2=CC=CC(=C2)OC)C3=CC=CC(=C3)OC
• Uses: suzuki reaction

Technology Process of Tris(3-methoxyphenyl)phosphine

There total 6 articles about Tris(3-methoxyphenyl)phosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

(3-methoxyphenyl)zinc(II) bromide (181705-90-8) → tris(3-methoxyphenyl)phosphine (29949-84-6)

Guidance literature:

With phosphorus trichloride; In acetonitrile; at 20 ℃; for 2h;

DOI:10.1055/s-2006-939056

Reference yield:

3-methoxy-1-iodobenzene (766-85-8) → tris(3-methoxyphenyl)phosphine (29949-84-6) + tetrakis(3-methoxyphenyl)phosphonium iodide

Guidance literature:

With dihydrogen phosphide sodium; C₁₄H₁₈FN₅; triethylamine; In acetonitrile; at 20 ℃; for 24h; Reagent/catalyst; Sealed tube; Irradiation; Schlenk technique; Glovebox; Inert atmosphere;

DOI:10.1002/anie.202110619

Reference yield:

3-methoxyphenyl bromide (2398-37-0) → tris(3-methoxyphenyl)phosphine (29949-84-6)

Guidance literature:

With phosphorus trichloride; In diethyl ether;

upstream raw materials:

(3-methoxyphenyl)magnesium bromide

3-methoxyphenyl bromide

(3-methoxyphenyl)zinc(II) bromide

tris(3-methoxyphenyl)phosphane oxide

Downstream raw materials:

2,2,2-Tris-(3-methoxy-phenyl)-4,4,5,5-tetramethyl-2λ⁵-[1,3,2]dioxaphospholane

Bis-(3-methoxy-phenyl)-phosphane

C₁₄H₁₄O₂P^(1-)*Na⁽¹⁺⁾

Tris-(m-anisyl)-fluorenyl-⁽⁹⁾-phosphoniumbromid

Refernces

• 1、 Davis, Matthew C.,Garrison, Michael D.,Ghiassi, Kamran B.,Groshens, Thomas J.,Redeker, Neil D.. "Flame retardant polycyanurate thermosets from the cyanate esters of triphenylphosphine oxide". . p. 1100 - 1110. Retrieved 2018/03/21.
• 2、 Le Gall, Erwan,Ben A?ssi, Karima,Lachaise, Isabelle,Troupel, Michel. "Synthesis of symmetrical and unsymmetrical functionalized arylphosphines from chlorophosphines and organozinc reagents". . p. 954 - 956. Retrieved 2007/10/03.