2,3-diphosphonooxypropanoic acid

Base Information

• Chemical Name: 2,3-diphosphonooxypropanoic acid
• CAS No.: 14438-19-8
• Molecular Formula: C3H8 O10 P2
• Molecular Weight: 266.038
• Hs Code.: 2931900090
• Mol file: 14438-19-8.mol

Synonyms:Glycericacid, bis(dihydrogen phosphate), D- (8CI); Propanoic acid,2,3-bis(phosphonooxy)-, (R)-; 2,3-Bisphospho-D-glyceric acid;2,3-Diphospho-D-glyceric acid; D-Glyceric acid bis(dihydrogen phosphate)

Chemical Property of 2,3-diphosphonooxypropanoic acid

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 669.8°Cat760mmHg
• Flash Point: 358.9°C
• PSA: 190.44000
• Density: 2.143g/cm³
• LogP: -1.34180

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3-diphosphonooxypropanoic acid

There total 3 articles about 2,3-diphosphonooxypropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

methyl 2,3-diphospho-D-glycerate → 2,3-diphospho-D-glyceric acid (14438-19-8) + cyclo-2,3-diphospho-D-glycerate

Guidance literature:

With pyridine; dicyclohexyl-carbodiimide; In acetonitrile; at 20 ℃; for 20h; lyophylization;

DOI:10.1016/0040-4039(95)02154-X

Reference yield:

(R)-2,3-bis-diphenoxyphosphoryloxy-propionic acid methyl ester → 2,3-diphospho-D-glyceric acid (14438-19-8)

Guidance literature:

With acetic acid; platinum; Hydrogenation_.bei Behandlung des Reaktionspropdukts mit wss. Natronlauge;

DOI:10.1080/00220480309595211

Reference yield:

→ 2,3-diphospho-D-glyceric acid (14438-19-8)

Guidance literature:

bei der Glykolyse im Blut von Menschen und Hunden;

Downstream raw materials:

2-oxo-propionic acid

D-(+)-2-phosphoglyceric acid

D-(-)-3-phosphoglyceric acid

D-glyceric acid

Refernces

• 1、 Towne,Rodwell,Grisolia. "". . p. 13. Retrieved 1958.