Benzophenone, 4-nitro-, oxime

Base Information

• Chemical Name: Benzophenone, 4-nitro-, oxime
• CAS No.: 38032-13-2
• Molecular Formula: C13H10N2O3
• Molecular Weight: 242.234
• Hs Code.: 2928000090
• Nikkaji Number: J308.182F
• Mol file: 38032-13-2.mol

Synonyms:Benzophenone, 4-nitro-, oxime;38032-13-2;(NZ)-N-[(4-nitrophenyl)-phenylmethylidene]hydroxylamine;p-Nitrobenzophenoneoxime;Methanone, (4-nitrophenyl)phenyl-, oxime

Chemical Property of Benzophenone, 4-nitro-, oxime

Chemical Property:

• Vapor Pressure: 7.68E-08mmHg at 25°C
• Boiling Point: 421°Cat760mmHg
• Flash Point: 208.4°C
• PSA: 78.41000
• Density: 1.25g/cm³
• LogP: 3.34460
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 242.06914219
• Heavy Atom Count: 18
• Complexity: 311

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=NO)C2=CC=C(C=C2)[N+](=O)[O-]
• Isomeric SMILES: C1=CC=C(C=C1)/C(=N/O)/C2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of Benzophenone, 4-nitro-, oxime

There total 3 articles about Benzophenone, 4-nitro-, oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitrobenzophenone (1144-74-7) → (4-nitrophenyl)(phenyl)methanone oxime (38032-13-2)

Guidance literature:

With hydroxylamine hydrochloride; Yield given;

DOI:10.1016/S0040-4039(00)78178-0

Reference yield:

nitrobenzene (98-95-3,26969-40-4) → (4-nitrophenyl)(phenyl)methanone oxime (38032-13-2)

Guidance literature:

Multi-step reaction with 2 steps

1: aluminum (III) chloride / 6 h / Reflux

2: sodium hydroxide; hydroxylamine hydrochloride / water; ethanol / 75 °C

With aluminum (III) chloride; hydroxylamine hydrochloride; sodium hydroxide; In ethanol; water; 1: |Friedel-Crafts Acylation;

DOI:10.1155/2015/435219

Reference yield:

benzoyl chloride (98-88-4) → (4-nitrophenyl)(phenyl)methanone oxime (38032-13-2)

Guidance literature:

Multi-step reaction with 2 steps

1: aluminum (III) chloride / 6 h / Reflux

2: sodium hydroxide; hydroxylamine hydrochloride / water; ethanol / 75 °C

With aluminum (III) chloride; hydroxylamine hydrochloride; sodium hydroxide; In ethanol; water; 1: |Friedel-Crafts Acylation;

DOI:10.1155/2015/435219

upstream raw materials:

4-nitrobenzophenone

nitrobenzene

benzoyl chloride

Downstream raw materials:

4-nitrobenzanilide

p-nitrobenzanilide

C₃₁H₃₂N₄O₇

C₂₁H₁₇N₃O₄

Refernces

• 1、 Zhang, Lin-hua,Ma, Philip. "Facile Detosylation of Cyclic Peptides. An Effective Synthesis of Platelet Glycoprotein IIb/IIIa Inhibitors". . p. 5765 - 5768. Retrieved 2007/10/02.