N-(Hydroxymethyl)stearamide

Base Information

• Chemical Name: N-(Hydroxymethyl)stearamide
• CAS No.: 3370-35-2
• Deprecated CAS: 110445-01-7,246523-42-2,246523-42-2
• Molecular Formula: C19H39NO2
• Molecular Weight: 313.524
• Hs Code.: 2924199090
• European Community (EC) Number: 222-147-1
• NSC Number: 3148
• UNII: FRM7G7A444
• DSSTox Substance ID: DTXSID3062998
• Nikkaji Number: J106.808C
• Wikidata: Q81990415
• Mol file: 3370-35-2.mol

Synonyms:N-(Hydroxymethyl)stearamide;3370-35-2;n-(hydroxymethyl)octadecanamide;Methylolstearamide;N-Methylolstearamide;Octadecanamide, N-(hydroxymethyl)-;Nalan RF;FRM7G7A444;NSC 3148;NSC-3148;EINECS 222-147-1;AI3-18377;N-HYDROXYMETHYL-STEARAMIDE;NSC3148;methylol stearamide;n-methylol stearamide;Stearinsauremethylolamid;UNII-FRM7G7A444;SCHEMBL226194;N-hydroxymethyl-n-octadecanamide;DTXSID3062998;N-(HYDROXYMETHYL)-OCTADECANAMIDE;FT-0628906;A875213;N-(hydroxymethyl)octadecanamide;Methylol stearamide

Chemical Property of N-(Hydroxymethyl)stearamide

Chemical Property:

• Vapor Pressure: 1.23E-10mmHg at 25°C
• Melting Point: >107 ℃
• Refractive Index: 1.463
• Boiling Point: 465.9 °C at 760 mmHg
• PKA: 13.40±0.10(Predicted)
• Flash Point: 235.5 °C
• PSA: 49.33000
• Density: 0.907 g/cm³
• LogP: 5.70480
• Storage Temp.: 2-8°C
• XLogP3: 7.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 17
• Exact Mass: 313.298079487
• Heavy Atom Count: 22
• Complexity: 232

Purity/Quality:

99.9% ^*data from raw suppliers

N-(Hydroxymethyl)stearamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCCCC(=O)NCO

Technology Process of N-(Hydroxymethyl)stearamide

There total 2 articles about N-(Hydroxymethyl)stearamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + stearamide (124-26-5) → N-methylol stearamide (3370-35-2)

Guidance literature:

Reference yield:

→ N-methylol stearamide (3370-35-2)

Guidance literature:

Stearinamid, Paraformaldehyd, i-PrOH, wss. KOH, 60grad;

DOI:10.1021/jo01070a094

Reference yield:

N-methylol stearamide (3370-35-2) → stearic acid (57-11-4)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrachloromethane; acetic acid; phosphorus trichloride / beim Erwaermen des Reaktionsprodukts mit 8prozentiger HCl auf 50grad

2: 70 - 80 °C

With tetrachloromethane; acetic acid; phosphorus trichloride;

upstream raw materials:

formaldehyd

stearamide

Downstream raw materials:

N-Ethoxymethyl-octadecansaeureamid

bis-stearoylamino-methane

1-(stearoylamino-methyl)-pyridinium; chloride

stearic acid