1,1-dicyano-2-(2,2-diphenylvinyl)-3,3-diisopropylcyclopropane

Base Information

• Chemical Name: 1,1-dicyano-2-(2,2-diphenylvinyl)-3,3-diisopropylcyclopropane
• CAS No.: 121730-86-7
• Molecular Formula: C₂₅H₂₆N₂
• Molecular Weight: 354.495
• Mol file: 121730-86-7.mol

Synonyms:1,1-dicyano-2-(2,2-diphenylvinyl)-3,3-diisopropylcyclopropane

Chemical Property of 1,1-dicyano-2-(2,2-diphenylvinyl)-3,3-diisopropylcyclopropane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1-dicyano-2-(2,2-diphenylvinyl)-3,3-diisopropylcyclopropane

There total 9 articles about 1,1-dicyano-2-(2,2-diphenylvinyl)-3,3-diisopropylcyclopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

1,1-dicyano-5,5-diphenyl-3,3-diisopropyl-1,4-pentadiene (121730-85-6) → Isopropylmalonsauredinitril (23741-79-9) + 1-phenyl-3-isopropylnaphthalene (121730-93-6) + 1,1-dicyano-5,5-diphenyl-3-isopropyl-1,4-pentadiene (121730-91-4) + 1,1-dicyano-2-(2,2-diphenylvinyl)-3,3-diisopropylcyclopropane (121730-86-7) + 2-(2,2-dicyanovinyl)-cis-1,3-diphenyl-cis-1,2-disiopropylcyclopropane + 4-(1,1-dicyano-2-methylpropyl)-1-phenyl-3-isopropyl-1,4-dihydronaphthalene (121730-94-7)

Guidance literature:

In acetonitrile; at 23 ℃; for 1.5h; Quantum yield; Mechanism; Product distribution; Irradiation; also in the presence of acetophenone, thioxanthone or xanthone as sensitizer;

DOI:10.1021/jo00277a013

Reference yield: 18.0%

1,1-dicyano-5,5-diphenyl-3,3-diisopropyl-1,4-pentadiene (121730-85-6) → 1,1-dicyano-2-(2,2-diphenylvinyl)-3,3-diisopropylcyclopropane (121730-86-7)

Guidance literature:

With acetophenone; In acetonitrile; at 23 ℃; for 0.166667h; Irradiation;

DOI:10.1021/jo00277a013

Reference yield:

4,4-diphenyl-2,2-diisopropyl-3-buten-1-ol (121730-83-4) → 1,1-dicyano-2-(2,2-diphenylvinyl)-3,3-diisopropylcyclopropane (121730-86-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / pyridinium chlorochromate / CH₂Cl₂ / 8.5 h

2: 225 mg / acetophenone / benzene / 0.67 h / Irradiation

3: 1.) 1.5 M n-butyllithium / 1.) THF, hexane, -78 deg C, 20 min, 2.) -78 deg C, 30 min

With n-butyllithium; acetophenone; pyridinium chlorochromate; In dichloromethane; benzene;

DOI:10.1021/jo00277a013

upstream raw materials:

diethyl (diphenylmethyl)phosphonate

2,2-dicyano-3,3-diisopropylcyclopropanecarboxaldehyde

1,1-dicyano-5,5-diphenyl-3,3-diisopropyl-1,4-pentadiene

2-(2,4-dimethylpentan-3-ylidene)malononitrile

Refernces