quinolin-2-yl(butylamino)methyldiphenylphosphine oxide

Base Information

• Chemical Name: quinolin-2-yl(butylamino)methyldiphenylphosphine oxide
• CAS No.: 1335204-96-0
• Molecular Formula: C₂₆H₂₇N₂OP
• Molecular Weight: 414.487
• Mol file: 1335204-96-0.mol

Synonyms:quinolin-2-yl(butylamino)methyldiphenylphosphine oxide

Chemical Property of quinolin-2-yl(butylamino)methyldiphenylphosphine oxide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of quinolin-2-yl(butylamino)methyldiphenylphosphine oxide

There total 2 articles about quinolin-2-yl(butylamino)methyldiphenylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

quinoline 2-carbaldehyde (5470-96-2) → quinolin-2-yl(butylamino)methyldiphenylphosphine oxide (1335204-96-0)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene / 1 h / Reflux

2: toluene / 2 h / Reflux

In toluene;

DOI:10.1002/hc.20704

Reference yield:

C14H16N2 + Diphenylphosphine oxide (4559-70-0) → quinolin-2-yl(butylamino)methyldiphenylphosphine oxide (1335204-96-0)

Guidance literature:

In toluene; for 2h; Reflux;

DOI:10.1002/hc.20704

Reference yield: 80.0%

methanol (67-56-1) + quinolin-2-yl(butylamino)methyldiphenylphosphine oxide (1335204-96-0) → quinoline 2-carbaldehyde (5470-96-2) + methyl diphenylphosphinate (1706-90-7)

Guidance literature:

quinolin-2-yl(butylamino)methyldiphenylphosphine oxide; With bromine; In chloroform;

methanol; With water; at 20 ℃; for 5h;

DOI:10.1002/hc.20704

upstream raw materials:

quinoline 2-carbaldehyde

Diphenylphosphine oxide

Downstream raw materials:

quinoline 2-carbaldehyde

methyl diphenylphosphinate

N-(quinolin-2-ylmethyl)-N-benzylamine

quinolin-2-yl(benzylamino)methyldiphenylphosphine oxide

Refernces