Technology Process of Pindone
There total 6 articles about Pindone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dichloro bis(acetonitrile) palladium(II); potassium phosphate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene;
In
dimethyl sulfoxide;
at 95 ℃;
for 24h;
Sealed tube;
Inert atmosphere;
DOI:10.1021/acs.joc.5b01758
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: thionyl chloride / 4 h / 80 °C
2.1: lithium hexamethyldisilazane / toluene / 3 h / 0 °C / Inert atmosphere
2.2: 5 h / Inert atmosphere
3.1: dichloro bis(acetonitrile) palladium(II); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; potassium phosphate / dimethyl sulfoxide / 24 h / 95 °C / Sealed tube; Inert atmosphere
With
dichloro bis(acetonitrile) palladium(II); potassium phosphate; thionyl chloride; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; lithium hexamethyldisilazane;
In
dimethyl sulfoxide; toluene;
DOI:10.1021/acs.joc.5b01758
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: lithium hexamethyldisilazane / toluene / 3 h / 0 °C / Inert atmosphere
1.2: 5 h / Inert atmosphere
2.1: dichloro bis(acetonitrile) palladium(II); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; potassium phosphate / dimethyl sulfoxide / 24 h / 95 °C / Sealed tube; Inert atmosphere
With
dichloro bis(acetonitrile) palladium(II); potassium phosphate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; lithium hexamethyldisilazane;
In
dimethyl sulfoxide; toluene;
DOI:10.1021/acs.joc.5b01758
