dibenzyl vinylphosphonate

Base Information

• Chemical Name: dibenzyl vinylphosphonate
• CAS No.: 7283-64-9
• Molecular Formula: C₁₆H₁₇O₃P
• Molecular Weight: 288.283
• Mol file: 7283-64-9.mol

Synonyms:dibenzyl vinylphosphonate

Chemical Property of dibenzyl vinylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dibenzyl vinylphosphonate

There total 3 articles about dibenzyl vinylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

vinyldichlorophosphine oxide (1438-74-0) + benzyl alcohol (100-51-6,185532-71-2) → dibenzyl vinylphosphonate (7283-64-9)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 20 ℃; for 0.25h; Inert atmosphere;

DOI:10.1002/chem.202003947

Reference yield:

benzyl alcohol (100-51-6,185532-71-2) → dibenzyl vinylphosphonate (7283-64-9)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / diethyl ether / 2 h / Ambient temperature

2: KOH / ethanol / 1 h / 0 °C

With potassium hydroxide; triethylamine; In diethyl ether; ethanol;

DOI:10.1002/hlca.19850680402

Reference yield:

benzyl alcohol (100-51-6,185532-71-2) → dibenzyl vinylphosphonate (7283-64-9)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine; diethyl ether

2: triethylamine

With pyridine; diethyl ether; triethylamine;

upstream raw materials:

benzyl alcohol

vinyldichlorophosphine oxide

Downstream raw materials:

vinylphosphonic acid

dibenzyl 4,5,6-tri-O-benzyl-8-O-(dibenzyloxyphosphoryl)-1,2,3-trideoxy-3-nitro-α-D-altro-3-octulopyranose-1-phosphonate

dibenzyl 4,5,6-tri-O-benzyl-8-O-(dibenzyloxyphosphoryl)-1,2-dideoxy-D-altro-3-octulopyranose-1-phosphonate

dibenzyl 4,5,6-tri-O-benzyl-1,2,3-trideoxy-3-nitro-α-D-altro-octulopyranose-1-phosphonate

Refernces

• 1、 Hauser, Anett,Poulou, Eleftheria,Müller, Fabian,Schmieder, Peter,Hackenberger, Christian P. R.. "Synthesis and Evaluation of Non-Hydrolyzable Phospho-Lysine Peptide Mimics". supporting information. p. 2326 - 2331. Retrieved 2020/12/09.