Methylmercury chloride

Base Information

• Chemical Name: Methylmercury chloride
• CAS No.: 115-09-3
• Molecular Formula: CH3 Cl Hg
• Molecular Weight: 251.078
• Hs Code.: 28521000
• European Community (EC) Number: 204-064-2
• NSC Number: 19998
• UN Number: 2025,3082
• DSSTox Substance ID: DTXSID5020813
• Wikidata: Q21010649
• Mol file: 115-09-3.mol

Synonyms:methyl mercury chloride;methylmercuric chloride;methylmercuric chloride, 203Hg-labeled;methylmercury chloride

Chemical Property of Methylmercury chloride

Chemical Property:

• Appearance/Colour: white crystals or powder
• Melting Point: 170-173 °C(lit.)
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 0.00000
• Density: g/cm³
• LogP: 1.27080
• Solubility.: Miscible with lipid.
• Water Solubility.: Soluble in organic solvents, alcohol and acetone. Slightly soluble in water. Insoluble in benzene
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 251.962971
• Heavy Atom Count: 3
• Complexity: 4.8
• Transport DOT Label: Poison

Purity/Quality:

98%min ^*data from raw suppliers

Methylmercury(II) chloride Cl ~13?% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T+,N
• Statements: 26/27/28-33-50/53
• Safety Statements: 13-28-36-45-60-61

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Metals -> Metals, Organic Compounds
• Canonical SMILES: C[Hg]Cl
• Uses: industrial and agricultural uses of the compound and its industrial production have generally been abandoned because of its high toxicity. Methylmercury remains of considerable concern, however, because of its continuous formation in the environment. In the aquatic environment, elemental mercury is first oxidized to the mercuric mercury ion (Hg2+ ), which may then become methylated to form methylmercury compounds, either by chemical or microbiologically catalyzed reactions. Methylmercury is accumulated by fish and marine mammals and attains its highest concentrations in large predatory species at the top of the aquatic and marine food chains. By this means, methylmercury enters the human diet. Thus, minimization of environmental mercury contamination is imperative. Methylmercury(II) chloride is used as a precursor for the preparation of methyl mercury acetate. It is used as a specific reagent (electron stain) for sulfhydryl groups in biological materials like protein as well as demonstration in electron microscopy.

Technology Process of Methylmercury chloride

There total 67 articles about Methylmercury chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

[(C5H5)2Ti(C6H4OCH3)(CH3)] (86822-34-6) + mercury dichloride → bis(cyclopentadienyl)methyltitanium(IV) chloride (1278-83-7) + [(C5H5)2TiCl(C6H4OCH3)] (86822-33-5) + methylmercury(II) chloride (115-09-3) + p-anisylmercuric chloride (3009-79-8)

Guidance literature:

In [⁽²⁾H₆]acetone; to cold (-78 °C) soln. of Ti complex in acetone-d6 added soln. of HgCl2 in acetone-d6 under N2; warmed to room temp., monitored by NMR;

DOI:10.1021/om50004a026

Reference yield: 50.0%

methyl(1,4,8,11-tetramethyl-1,4,8,11-tetraazacyclotetradecane)nickel(II) + mercury dichloride → methylmercury(II) chloride (115-09-3)

Guidance literature:

In dimethyl sulfoxide;

DOI:10.1021/ja00113a032

Reference yield: 42.0%

[(C5H5)2Ti(C6H4CH3)(CH3)] (86822-35-7) + mercury dichloride → bis(cyclopentadienyl)methyltitanium(IV) chloride (1278-83-7) + [(C5H5)2TiCl(C6H4CH3)] (86822-29-9) + methylmercury(II) chloride (115-09-3) + 4-methylphenylmercuric chloride (539-43-5)

Guidance literature:

In [⁽²⁾H₆]acetone; to cold (-78 °C) soln. of Ti complex in acetone-d6 added soln. of HgCl2 in acetone-d6 under N2; warmed to room temp., monitored by NMR;

DOI:10.1021/om50004a026

upstream raw materials:

mercury(II) diacetate

dimethylmercury

trimethylaluminum

methylmagnesium bromide

Downstream raw materials:

dimethylmercury

tetramethylstannane

bis(cyclopentadienyl)methyltitanium(IV) chloride

methyl phenyl mercury

Refernces

• 1、 . "-". . p. 1019 - 1025. Retrieved 1950.
• 2、 Rego, Christopher A.,Cox, A. Peter. "". . p. 595 - 602. Retrieved 1987.
• 3、 Brisdon, Alan K.,Crossley, Ian R.,Pritchard, Robin G.. "Asymmetric fluoro-alkynyl mercurials: The synthesis and solid state structures of RHgC=CCF3 (R = Ph, Fc)". . p. 5487 - 5490. Retrieved 2005.
• 4、 Joseph, Michael F.,Page, John A.,Baird, Michael C.. "Oxidative cleavage reactions of compounds of the type CpRuLL′R (L, L′ = CO, PPh3; R = Me, PhCH2)". . p. 1749 - 1754. Retrieved 1984.
• 5、 Hayashi et al.. "". . p. 158. Retrieved 1977.