N-trifluoroacetyl acetanilide

Base Information

• Chemical Name: N-trifluoroacetyl acetanilide
• CAS No.: 361-11-5
• Molecular Formula: C₁₀H₈F₃NO₂
• Molecular Weight: 231.174
• Mol file: 361-11-5.mol

Synonyms:N-trifluoroacetyl acetanilide

Chemical Property of N-trifluoroacetyl acetanilide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of N-trifluoroacetyl acetanilide

There total 2 articles about N-trifluoroacetyl acetanilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Acetanilid (103-84-4) + trifluoroacetic anhydride (407-25-0) → N-trifluoroacetyl acetanilide (361-11-5)

Guidance literature:

Reference yield:

acetophenone oxime (613-91-2) → N-trifluoroacetyl acetanilide (361-11-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 79.84 °C

2: acetonitrile / 1 h / 24.84 °C

In acetonitrile;

DOI:10.1016/j.apcata.2013.12.026

Reference yield:

2,5 dichloroaniline (95-82-9) + N-trifluoroacetyl acetanilide (361-11-5) → trifluoro-acetic acid-(2,5-dichloro-anilide) (328-11-0) + Acetanilid (103-84-4)

Guidance literature:

upstream raw materials:

Acetanilid

trifluoroacetic anhydride

acetophenone oxime

Downstream raw materials:

trifluoro-acetic acid-(2,5-dichloro-anilide)

Acetanilid

Refernces