α-(4-pyrimidyl)phenylacetonitrile

Base Information Edit

Chemical Name:α-(4-pyrimidyl)phenylacetonitrile
CAS No.:130532-95-5
Molecular Formula:C₁₂H₉N₃
Molecular Weight:195.224
Hs Code.:
Mol file:130532-95-5.mol

Synonyms:α-(4-pyrimidyl)phenylacetonitrile

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Chemical Property of α-(4-pyrimidyl)phenylacetonitrile Edit

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Technology Process of α-(4-pyrimidyl)phenylacetonitrile

There total 4 articles about α-(4-pyrimidyl)phenylacetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 134340-12-8
α(6-chloro-4-pyrimidyl)phenylacetonitril

: 130532-95-5
α-(4-pyrimidyl)phenylacetonitrile

Guidance literature:: With hydrogen; magnesium oxide; palladium on activated charcoal; In ethanol; water; under 760 Torr; Ambient temperature;

Reference yield:

: 140-29-4
phenylacetonitrile

: 130532-95-5
α-(4-pyrimidyl)phenylacetonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 1) NaNH₂ / 1) THF, 15 min, RT, 2) THF, 1 h, RT

2: 71 percent / H₂, MgO / 10percent Pd/C / ethanol; H₂O / 760 Torr / Ambient temperature

With hydrogen; magnesium oxide; sodium amide; palladium on activated charcoal; In ethanol; water;