2-(6-Methoxy-2-naphthyl)propionic acid

Base Information Edit

Chemical Name:2-(6-Methoxy-2-naphthyl)propionic acid
CAS No.:23981-80-8
Deprecated CAS:26159-31-9,1264273-58-6
Molecular Formula:C14H14O3
Molecular Weight:230.263
Hs Code.:29189900
European Community (EC) Number:247-485-7,245-969-2
DSSTox Substance ID:DTXSID70860274
Nikkaji Number:J242.713C,J9.289D
Wikidata:Q27163737
Pharos Ligand ID:6CXCL27JWX2P
ChEMBL ID:CHEMBL12952
Mol file:23981-80-8.mol

Synonyms:23981-80-8;2-(6-methoxynaphthalen-2-yl)propanoic acid;DL-Naproxen;2-(6-Methoxy-2-naphthyl)propionic acid;(+/-)-2-(6-Methoxy-2-naphthyl)propionic Acid;Racemic Naproxen;2-(6-Methoxy-2-naphthyl)propanoic acid;26159-31-9;rac-naproxen;(RS)-Naproxen;Naproxen (racemic);rac Naproxen-13C,d3;EINECS 245-969-2;MFCD00439456;( inverted exclamation markA)-Naproxen;alpha-(6-Methoxy-2-naphthyl)propionic acid;(+-)-2-(6-methoxy-2-naphthyl)propionic acid;2-(6-Methoxy-naphthalen-2-yl)-propionic acid;EC 247-485-7;(+/-)-6-Methoxy-alpha-methyl-2-naphthaleneacetic Acid;SMR001233475;rac Naproxen;EINECS 247-485-7;(1)-2-(6-Methoxy-2-naphthyl)propionic acid;6-methoxy-alpha-methyl-2-naphthaleneacetic acid;Prestwick3_000045;Naproxen2-(6-Methoxy-naphthalen-2-yl)-propionic acid;2-(6-Methoxy-naphthalen-2-yl)-propionic acid(Naproxen);Oprea1_018821;BSPBio_000169;2-naphthaleneacetic acid, 6-methoxy-alpha-methyl-;MLS002154184;MLS006011863;CHEMBL12952;SCHEMBL145769;BPBio1_000187;SCHEMBL10029028;CHEBI:91939;DTXSID70860274;HMS2095I11;HMS2230K21;HMS3374N03;HMS3712I11;BBL038237;BDBM50009860;STK301546;AKOS000121315;AKOS016038194;CCG-220045;CS-O-10952;CS-W009085;2-(6-methoxy-2-naphtyl)propionic acid;NCGC00021127-02;NCGC00021127-03;NCGC00021127-04;NCGC00021127-05;NCGC00094733-01;NCGC00094733-02;NCGC00094733-03;2-(6-methoxy-2-naphthyl)-propionic acid;2-(6-methoxynaphth-2-yl)-propionic acid;AC-25684;AS-47598;HY-15029;2-(6-methoxynaphthalen-2-yl)propanoicacid;2-(6-methoxy-2-naphthalenyl)propanoic acid;6-methoxy-2naphthyl-alpha-methylacetic acid;LS-187192;2-(6-Methoxynaphthalene-2-yl)propanoic acid;6-methoxy-2-naphthyl-alpha-methylacetic acid;6-methoxy-alpha-methyl-2-naphthylacetic acid;AB00513799;FT-0602835;FT-0605171;FT-0638374;M1220;(+)2-(6-methoxy-2-naphthyl) propionic acid;EN300-21613;6-methoxy-alpha-methyl-2-naphthalenacetic acid;6-Methoxy-alpha-methyl-2-naphthaleneessigsaure;F14583;(+)-alpha-(6-methoxy-2-naphthyl)propionic acid;racemic 2-(6-methoxy-2-naphthyl)propionic acid;(+)-alpha-methyl-6-methoxy-2-naphthylacetic acid;(+/-)-2-(6-methoxy-2-naphthyl) propionic acid;(RS)-2-(6-methoxynaphthalen-2-yl)propanoic acid;2-(6-Methoxy-2-naphthyl)propanoic acid, AldrichCPR;Q-201030;(+)-(S)-6-Methoxy-a-methyl-2-naphthaleneacetic acid;BRD-A87719232-001-02-4;Q27163737;Z104505002;MSNT?1-(Mesitylene-2-sulfonyl)-3-nitro-1,2,4-triazole

Suppliers and Price of 2-(6-Methoxy-2-naphthyl)propionic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
rac-Naproxen
10g
$ 215.00

TRC
rac-Naproxen
5g
$ 110.00

TCI Chemical
(±)-2-(6-Methoxy-2-naphthyl)propionic Acid >98.0%(GC)(T)
5g
$ 55.00

TCI Chemical
(±)-2-(6-Methoxy-2-naphthyl)propionic Acid >98.0%(GC)(T)
25g
$ 243.00

Sigma-Aldrich
Naproxen (racemic) European Pharmacopoeia (EP) Reference Standard
y0000399
$ 190.00

Sigma-Aldrich
rac-Naproxen Pharmaceutical Secondary Standard; Certified Reference Material
100MG
$ 149.00

Oakwood
2-(6-Methoxy-2-naphthyl)propionicacid 97%
1g
$ 14.00

Medical Isotopes, Inc.
rac-Naproxen
10 g
$ 675.00

Medical Isotopes, Inc.
rac-Naproxen
1 g
$ 610.00

Matrix Scientific
2-(6-Methoxy-2-naphthyl)propionic acid 97%
1g
$ 102.00

Total 54 raw suppliers

Chemical Property of 2-(6-Methoxy-2-naphthyl)propionic acid Edit

Chemical Property:

Appearance/Colour:White solid
Melting Point:157 °C
Boiling Point:403.9 °C at 760 mmHg
PKA:4.84±0.30(Predicted)
Flash Point:154.5 °C
PSA：46.53000
Density:1.198 g/cm³
LogP:3.03650
Storage Temp.:Refrigerator
Solubility.:soluble in Methanol
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:230.094294304
Heavy Atom Count:17
Complexity:277

Purity/Quality:

98%,99%, ^*data from raw suppliers

rac-Naproxen ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/37/38-36
Safety Statements: 26-36/37/39-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O
Uses An anti-inflammatory, analgesic, antipyretic. A non-steroidal anti-inflammatory.

Technology Process of 2-(6-Methoxy-2-naphthyl)propionic acid

There total 155 articles about 2-(6-Methoxy-2-naphthyl)propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: vinyl 2-(6-methoxy-2-naphthyl)propionate

: 23981-80-8
naproxen

Guidance literature:: With water; dichloro bis(acetonitrile) palladium(II); at 40 ℃; for 1h;
DOI:10.1016/j.jorganchem.2006.06.045

Reference yield: 99.0%

: 201230-82-2
carbon monoxide

: 72775-41-8
1-chloro-1-(6'-methoxy-2'-naphthyl)-ethane

: 23981-80-8
naproxen

Guidance literature:: With water; toluene-4-sulfonic acid; triphenylphosphine; lithium chloride; 1% Rh/C; In butanone; at 115 ℃; under 41372.9 Torr;

Reference yield: 99.0%

: 201230-82-2
carbon monoxide

: 108781-65-3,119341-64-9,125712-80-3,77301-42-9
1-(6-methoxy-2-naphthyl)ethanol

: 23981-80-8
naproxen

Guidance literature:: With water; toluene-4-sulfonic acid; triphenylphosphine; lithium chloride; 1% Rh/C; In butanone; at 115 ℃; under 41372.9 Torr;