3-Acetoxy-17β-sulfooxyestra-1,3,5(10)-triene triethylammonium salt

Base Information

• Chemical Name: 3-Acetoxy-17β-sulfooxyestra-1,3,5(10)-triene triethylammonium salt
• CAS No.: 29362-60-5
• Molecular Formula: C₆H₁₅N*C₂₀H₂₆O₆S
• Molecular Weight: 495.681
• Mol file: 29362-60-5.mol

Synonyms:3-Acetoxy-17β-sulfooxyestra-1,3,5(10)-triene triethylammonium salt

Chemical Property of 3-Acetoxy-17β-sulfooxyestra-1,3,5(10)-triene triethylammonium salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Acetoxy-17β-sulfooxyestra-1,3,5(10)-triene triethylammonium salt

There total 2 articles about 3-Acetoxy-17β-sulfooxyestra-1,3,5(10)-triene triethylammonium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

estradiol 3-acetate (4245-41-4) + triethylamine sulfur trioxide (761-01-3,54381-28-1) → 3-Acetoxy-17β-sulfooxyestra-1,3,5(10)-triene triethylammonium salt (29362-60-5)

Guidance literature:

In pyridine; for 3h; Yield given; Ambient temperature;

DOI:10.1016/0039-128X(85)90079-0

Reference yield:

estradiol (50-28-2) + acetic anhydride (108-24-7) + triethylamine sulfur trioxide (761-01-3,54381-28-1) → 3-Acetoxy-17β-sulfooxyestra-1,3,5(10)-triene triethylammonium salt (29362-60-5)

Guidance literature:

Yield given. Multistep reaction; 1) pyridine, r.t., 2 h, 2) pyridine, r.t., overnight;

DOI:10.1016/0039-128X(85)90079-0

Reference yield:

3-Acetoxy-17β-sulfooxyestra-1,3,5(10)-triene triethylammonium salt (29362-60-5) → 3-Benzoyloxy-17β-sulfooxyestra-1,3,5(10)-triene triethylammonium salt (105546-96-1)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / methanol / Heating

2: pyridine / Ambient temperature

With triethylamine; In pyridine; methanol;

DOI:10.1016/0039-128X(85)90079-0

upstream raw materials:

estradiol 3-acetate

triethylamine sulfur trioxide

estradiol

acetic anhydride

Downstream raw materials:

3-Benzoyloxy-17β-sulfooxyestra-1,3,5(10)-triene triethylammonium salt

Refernces