6alpha-Oxycodol

Base Information Edit

Chemical Name:6alpha-Oxycodol
CAS No.:7183-69-9
Molecular Formula:C18H23NO4
Molecular Weight:317.385
Hs Code.:
European Community (EC) Number:682-866-5
UNII:75CDM1Q08M
DSSTox Substance ID:DTXSID10222115
Nikkaji Number:J55.439A
Wikipedia:14-Hydroxydihydrocodeine
Wikidata:Q13548811
ChEMBL ID:CHEMBL2008168
Mol file:7183-69-9.mol

Synonyms:6alpha-Oxycodol;Dihydrooxycodone;7183-69-9;14-Hydroxydihydrocodeine;6-alpha-Oxycodol;Dihydrohydroxycodeine-A;Dihydrohydroxycodeine-B;Dihydrohydroxycodeine-C;Codeine-C, dihydrohydroxy;Codeine-A, dihydrohydroxy-;Codeine, 7,8-dihydro-14-hydroxy-;RAM-318;UNII-75CDM1Q08M;CODEINE B, DIHYDRO-14-HYDROXY-;75CDM1Q08M;(4R,4aS,7S,7aR,12bS)-9-methoxy-3-methyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7-diol;4,5-alpha-Epoxy-3-methoxy-17-methylmorphinan-6-alpha,14-diol;Morphinan-6-alpha,14-diol, 4,5-alpha-epoxy-3-methoxy-17-methyl-;6??-Oxycodol;Morphinan-6,14-diol, 4,5-epoxy-3-methoxy-17-methyl-, (5-alpha,6-alpha)-;Morphinan-6,14-diol, 4,5-epoxy-3-methoxy-17-methyl-, (5.alpha.,6.alpha.)-;6.ALPHA.-OXYCODOL;6-.ALPHA. OXYCODOL;CHEMBL2008168;DTXSID10222115;LHTAJTFGGUDLRH-QMVVXIJUSA-N;AKOS040758312;14-HYDROXY-7,8-DIHYDROCODEINE;LS-54630;PD057069;Q13548811;OXYCODONE HYDROCHLORIDE IMPURITY B [EP IMPURITY];OXYCODONE HYDROCHLORIDE, 6-.ALPHA. OXYCODOL- [USP IMPURITY]

Suppliers and Price of 6alpha-Oxycodol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
6α-Oxycodol ≥98%
5mg
$ 316.00

Cayman Chemical
6α-Oxycodol (CRM)
1mg
$ 213.00

Cayman Chemical
6α-Oxycodol ≥98%
1mg
$ 71.00

Total 10 raw suppliers

Chemical Property of 6alpha-Oxycodol Edit

Chemical Property:

Vapor Pressure:7.06E-11mmHg at 25°C
Boiling Point:501.5°C at 760 mmHg
PKA:13.49±0.40(Predicted)
Flash Point:257.1°C
PSA：62.16000
Density:1.4g/cm³
LogP:0.77790
XLogP3:-0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:317.16270821
Heavy Atom Count:23
Complexity:515

Purity/Quality:

99%, ^*data from raw suppliers

6α-Oxycodol ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC23C4C(CCC2(C1CC5=C3C(=C(C=C5)OC)O4)O)O
Isomeric SMILES:CN1CC[C@]23[C@@H]4[C@H](CC[C@]2([C@H]1CC5=C3C(=C(C=C5)OC)O4)O)O
Description 6α-Oxycodol (CRM) (Item No. 25938) is a certified reference material categorized as an opioid. 6α-Oxycodol is a metabolite of oxycodone (Item Nos. 15465 | ISO60148). This product is intended for research and forensic applications.
Uses 6α-Oxycodol is a dihydro metabolite of the analgesic opiate Oxycodone (O870600).

Technology Process of 6alpha-Oxycodol

There total 14 articles about 6alpha-Oxycodol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.4%

: 76-42-6
Oxycodone

: 7183-69-9
14-hydroxydihydrocodeine

Guidance literature:: With sodium triacetoxyborohydride; acetic acid; In methanol; at 15 - 20 ℃; for 24h;

Reference yield:

: 85390-93-8
3β,7β,15α-trihydroxy-5-androsten-17-one

: 82543-09-7
7β-hydroxy-15β,16β-methylene-3β-pivaloyloxy-5-androsten-17-one

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / 4-dimethylaminopyridine / pyridine / 4 h / 50 °C

2: 91 percent / NaOH / dimethylsulfoxide / 1 h / Ambient temperature

With dmap; sodium hydroxide; In pyridine; dimethyl sulfoxide;