1,4-Bis(bromomethyl)-2,5-dimethylbenzene

Base Information

• Chemical Name: 1,4-Bis(bromomethyl)-2,5-dimethylbenzene
• CAS No.: 35168-62-8
• Molecular Formula: C10H12 Br2
• Molecular Weight: 292.013
• Hs Code.: 2903999090
• European Community (EC) Number: 252-413-2
• DSSTox Substance ID: DTXSID10188661
• Nikkaji Number: J289.920E
• Wikidata: Q83060481
• Mol file: 35168-62-8.mol

Synonyms:1,4-Bis(bromomethyl)-2,5-dimethylbenzene;35168-62-8;EINECS 252-413-2;2,5-Bis(bromomethyl)-p-xylene;SCHEMBL3052064;YSZC3158;DTXSID10188661;MFCD04038409;AKOS025295200;1,4-dibromomethyl-2,5-dimethylbenzene;AC-27909;2,5-Dimethyl-1,4-bis(bromomethyl)benzene;B2210;FT-0639236;T70812;A822621

Chemical Property of 1,4-Bis(bromomethyl)-2,5-dimethylbenzene

Chemical Property:

• Vapor Pressure: 0.000878mmHg at 25°C
• Melting Point: 163 °C
• Boiling Point: 314.1°Cat760mmHg
• Flash Point: 165.8°C
• PSA: 0.00000
• Density: 1.613g/cm³
• LogP: 4.09320
• Solubility.: soluble in Toluene
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 291.92853
• Heavy Atom Count: 12
• Complexity: 120

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,4-Bis(bromomethyl)-2,5-dimethylbenzene >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Statements: 34
• Safety Statements: 36/37/39

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1CBr)C)CBr

Technology Process of 1,4-Bis(bromomethyl)-2,5-dimethylbenzene

There total 8 articles about 1,4-Bis(bromomethyl)-2,5-dimethylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + para-xylene (106-42-3) → 2,5-dibromomethyl-p-xylene (35168-62-8)

Guidance literature:

With hydrogen bromide; acetic acid; at 120 ℃; for 16h;

DOI:10.1039/c8ob01891j

Reference yield: 66.0%

1,3,5-Trioxan (110-88-3) + para-xylene (106-42-3) → 2,5-dibromomethyl-p-xylene (35168-62-8)

Guidance literature:

With hydrogen bromide; cetyltrimethylammonium bromide; acetic acid; for 24h; Heating;

DOI:10.1016/0040-4020(96)00540-6

Reference yield:

1,4-bis(hydroxymethyl)-2,5-dimethylbenzene (22530-09-2) → 2,5-dibromomethyl-p-xylene (35168-62-8)

Guidance literature:

With hydrogen bromide; at 100 ℃;

upstream raw materials:

1,4-bis(hydroxymethyl)-2,5-dimethylbenzene

1,3,5-Trioxan

para-xylene

1,2,4,5-tetramethylbenzene

Downstream raw materials:

2,5-dimethyl-1,4-phenylenediacetonitrile

tetraethyl ((2,5-dimethyl-1,4-phenylene)bis(methylene))bis(phosphonate)

1,4-bis(mercaptomethyl)-2,5-dimethylbenzene

1,1'-<2,5-dimethyl-1,4-phenylenebis(methylene)>bis<4,8,11-tris(p-tolylsulfonyl)-1,4,8,11-tetraazacyclotetradecane>

Refernces

• 1、 Song, Xue-Qin,Lei, Yao-Kun,Wang, Xiao-Run,Zhao, Meng-Meng,Peng, Yun-Qiao,Cheng, Guo-Quan. "Lanthanide coordination polymers: Synthesis, diverse structure and luminescence properties". . p. 202 - 212. Retrieved 2014.
• 2、 Hsu, Ting-Wei,Kim, Cheoljae,Michaudel, Quentin. "Stereoretentive Ring-Opening Metathesis Polymerization to Access All- cis Poly(p-phenylenevinylene)s with Living Characteristics". supporting information. p. 11983 - 11987. Retrieved 2020/08/06.
• 3、 Steemers, Luuk,Wanner, Martin J.,van Leeuwen, Bart R. C.,Hiemstra, Henk,van Maarseveen, Jan H.. "Attempted [2]Catenane Synthesis via a Quasi[1]catenane by a Templated Backfolding Strategy". supporting information. p. 874 - 878. Retrieved 2018/02/27.