N-(2-(Dimethylamino)ethyl)acrylamide

Base Information

• Chemical Name: N-(2-(Dimethylamino)ethyl)acrylamide
• CAS No.: 925-76-8
• Molecular Formula: C7H14N2O
• Molecular Weight: 142.201
• European Community (EC) Number: 213-124-7
• NSC Number: 135479
• UNII: DZB64P4DCF
• DSSTox Substance ID: DTXSID70239022
• Nikkaji Number: J298.490C
• Wikidata: Q83121359
• Mol file: 925-76-8.mol

Synonyms:925-76-8;N-(2-(Dimethylamino)ethyl)acrylamide;N-[2-(Dimethylamino)ethyl]acrylamide;N-(N,N-Dimethylamino)ethyl acrylamide;2-Propenamide, N-[2-(dimethylamino)ethyl]-;Acrylamide, N-(2-(dimethylamino)ethyl)-;N-[2-(dimethylamino)ethyl]prop-2-enamide;DZB64P4DCF;2-Propenamide, N-(2-(dimethylamino)ethyl)-;EINECS 213-124-7;NSC 135479;NSC-135479;Acrylamide, N-[2-(dimethylamino)ethyl]-;NSC135479;UNII-DZB64P4DCF;SCHEMBL27346;DTXSID70239022;N-(2-dimethylaminoethyl)acrylamide;ZAA59925;MFCD00053694;2-(dimethylamino)-N-ethyl acrylamide;N,N-DIMETHYLAMINOETHYL ACRYLAMIDE;N-[2-(Dimethylamino)ethyl]acrylamide #;AS-84381;D5794;F88649;A904598

Chemical Property of N-(2-(Dimethylamino)ethyl)acrylamide

Chemical Property:

• Vapor Pressure: 0.00817mmHg at 25°C
• Boiling Point: 267.4°C at 760 mmHg
• Flash Point: 115.5°C
• Density: 0.933g/cm³
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 142.110613074
• Heavy Atom Count: 10
• Complexity: 121

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCNC(=O)C=C

Technology Process of N-(2-(Dimethylamino)ethyl)acrylamide

There total 5 articles about N-(2-(Dimethylamino)ethyl)acrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

N-(2-dimethylaminoethyl)-3-methoxypropionamide (74302-23-1) → N-[2-(dimethylamino)ethyl]acrylamide (925-76-8)

Guidance literature:

With sodium hydroxide; In methanol;

Reference yield: 46.0%

N,N-dimethylethylenediamine (108-00-9) + acryloyl chloride (814-68-6,25189-84-8) → N-[2-(dimethylamino)ethyl]acrylamide (925-76-8)

Guidance literature:

With 2,6-di-tert-butyl-4-methyl-phenol; sodium carbonate; In dichloromethane; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1002/ejic.201601364

Reference yield:

N'-ethyl-N,N-dimethyl-hydrazine (29559-82-8) → N-[2-(dimethylamino)ethyl]acrylamide (925-76-8)

Guidance literature:

With PPA; In water;

upstream raw materials:

N'-ethyl-N,N-dimethyl-hydrazine

N-(2-dimethylaminoethyl)-3-methoxypropionamide

10H-phenothiazine

acryloyl chloride

Refernces

• 1、 Xu, Kun,An, Huiyong,Lu, Cuige,Tan, Ying,Li, Pengchong,Wang, Pixin. "Facile fabrication method of hydrophobic-associating cross-linking hydrogel with outstanding mechanical performance and self-healing property in the absence of surfactants". . p. 5665 - 5672. Retrieved 2013.
• 2、 -. "CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS". Page/Page column 53; 109. . Retrieved 2017/12/18.