Salmeterol

Base Information Edit

Chemical Name:Salmeterol
CAS No.:89365-50-4
Molecular Formula:C25H37NO4
Molecular Weight:415.573
Hs Code.:2922509090
European Community (EC) Number:618-267-2
UNII:2I4BC502BT
DSSTox Substance ID:DTXSID6023571
Nikkaji Number:J707.866H
Wikipedia:Salmeterol
Wikidata:Q424333
NCI Thesaurus Code:C29443
RXCUI:36117
Pharos Ligand ID:X3GGJ7GNYWXG
Metabolomics Workbench ID:145667
ChEMBL ID:CHEMBL1263
Mol file:89365-50-4.mol

Synonyms:salmeterol;salmeterol xinafoate;Serevent;Xinafoate, Salmeterol

Suppliers and Price of Salmeterol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Salmeterol
500ul
$ 280.00

TRC
Salmeterol
10mg
$ 130.00

Medical Isotopes, Inc.
Salmeterol
5 mg
$ 950.00

DC Chemicals
Salmeterol >98%
250 mg
$ 700.00

DC Chemicals
Salmeterol >98%
100 mg
$ 350.00

Crysdot
Salmeterol 98+%
50mg
$ 467.00

ChemScene
Salmeterol 99.88%
100mg
$ 600.00

ChemScene
Salmeterol 99.88%
10mg
$ 100.00

ChemScene
Salmeterol 99.88%
50mg
$ 350.00

Chemenu
4-(1-Hydroxy-2-((6-(4-phenylbutoxy)hexyl)amino)ethyl)-2-(hydroxymethyl)phenol 98%
50mg
$ 436.00

Total 98 raw suppliers

Chemical Property of Salmeterol Edit

Chemical Property:

Melting Point:75.5-76.5°
Boiling Point:603 °C at 760 mmHg
PKA:9.99±0.31(Predicted)
Flash Point:318.5 °C
PSA：81.95000
Density:1.112 g/cm³
LogP:4.49830
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
XLogP3:3.9
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:16
Exact Mass:415.27225866
Heavy Atom Count:30
Complexity:403

Purity/Quality:

99% ^*data from raw suppliers

Salmeterol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CCCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O
Recent ClinicalTrials:Single Blind Cross-over Dose Response Study in Subjects of Two Inhalers of Salmeterol and Fluticasone Propionate
Recent EU Clinical Trials:EFFECT OF ELECTRONIC MONITORING AND FEEDBACK ON ADHERENCE TO EASYHALER CONTROLLER MEDICATION IN PATIENTS WITH ASTHMA
Recent NIPH Clinical Trials:Evaluation of function of respiratory muscles using a fine wire electrodes under hypoxia, hypercapnia, posture changing, drugs and ventilator.
Uses Salmeterol is a β2-Adrenergic agonist used for relief and control of asthma symptoms.
Clinical Use Salmeterol usually is prescribed for severe persistent asthma following previous treatment with a short-acting β-agonist, such as albuterol. The noticeable differences between salmeterol and albuterol are the onset of action and their duration of action (Table 13.6). When used regularly every day as prescribed, inhaled albuterol decreases the number and severity of asthma attacks. It is not used, however, for relieving an asthma attack that has already started.

Technology Process of Salmeterol

There total 52 articles about Salmeterol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%