Technology Process of 5,6-dihydroxy-7-phenyl-1H-phenalen-1-one
There total 6 articles about 5,6-dihydroxy-7-phenyl-1H-phenalen-1-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium hypochlorite; Mn salen; 4-phenylpyridine N-oxide / sodium phosphate / CH2Cl2; H2O / 3 h / 0 °C
2: acetic acid; hydrobromic acid / 10 h / Heating
With
sodium hypochlorite; 4-Phenylpyridine 1-oxide; 2,2′-((1E,1′E)-(ethane-1,2-diylbis(azanylylidene))bis(methanylylidene))diphenolmanganese(II); hydrogen bromide; acetic acid;
sodium phosphate;
In
dichloromethane; water;
1: Jacobsen-Katsuki epoxidation;
DOI:10.1002/jlcr.808
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: phosphoric acid; boric acid; FeSO4 / glycerol / 0.58 h / 160 °C
2.1: ethanol / 20 °C
3.1: magnesium; iodine / tetrahydrofuran / 0.33 h
3.2: tetrahydrofuran / 0.25 h / -70 - 5 °C
3.3: 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / CH2Cl2 / 0.25 h / Heating
4.1: sodium hypochlorite; Mn salen; 4-phenylpyridine N-oxide / sodium phosphate / CH2Cl2; H2O / 3 h / 0 °C
5.1: acetic acid; hydrobromic acid / 10 h / Heating
With
sodium hypochlorite; 4-Phenylpyridine 1-oxide; 2,2′-((1E,1′E)-(ethane-1,2-diylbis(azanylylidene))bis(methanylylidene))diphenolmanganese(II); phosphoric acid; hydrogen bromide; iodine; boric acid; iron(II) sulfate; magnesium; acetic acid;
sodium phosphate;
In
tetrahydrofuran; ethanol; dichloromethane; water; glycerol;
3.2: Grignard reaction / 4.1: Jacobsen-Katsuki epoxidation;
DOI:10.1002/jlcr.808
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: ethanol / 20 °C
2.1: magnesium; iodine / tetrahydrofuran / 0.33 h
2.2: tetrahydrofuran / 0.25 h / -70 - 5 °C
2.3: 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / CH2Cl2 / 0.25 h / Heating
3.1: sodium hypochlorite; Mn salen; 4-phenylpyridine N-oxide / sodium phosphate / CH2Cl2; H2O / 3 h / 0 °C
4.1: acetic acid; hydrobromic acid / 10 h / Heating
With
sodium hypochlorite; 4-Phenylpyridine 1-oxide; 2,2′-((1E,1′E)-(ethane-1,2-diylbis(azanylylidene))bis(methanylylidene))diphenolmanganese(II); hydrogen bromide; iodine; magnesium; acetic acid;
sodium phosphate;
In
tetrahydrofuran; ethanol; dichloromethane; water;
2.2: Grignard reaction / 3.1: Jacobsen-Katsuki epoxidation;
DOI:10.1002/jlcr.808