Dicyclanil

Base Information

• Chemical Name: Dicyclanil
• CAS No.: 112636-83-6
• Molecular Formula: C8H10N6
• Molecular Weight: 190.208
• Hs Code.: 2933599090
• European Community (EC) Number: 601-192-4
• UNII: DBC8O809S5
• DSSTox Substance ID: DTXSID5041013
• Nikkaji Number: J1.681.763E
• Wikidata: Q27276312
• Mol file: 112636-83-6.mol

Synonyms:4,6-Diamino-2-cyclopropylaminopyrimidine-5-carbonitrile;dicyclanil

Chemical Property of Dicyclanil

Chemical Property:

• Appearance/Colour: White microcrystalline powder
• Vapor Pressure: 7.04E-12mmHg at 25°C
• Melting Point: 250.5-252.4oC
• Refractive Index: 1.68
• Boiling Point: 543.639 °C at 760 mmHg
• PKA: 4.09±0.50(Predicted)
• Flash Point: 282.583 °C
• PSA: 113.64000
• Density: 1.449 g/cm³
• LogP: 1.32238
• Storage Temp.: 0-6°C
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 190.09669434
• Heavy Atom Count: 14
• Complexity: 242

Purity/Quality:

99% ^*data from raw suppliers

Dicyclanil ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn, N
• Hazard Codes: Xn;N,N,Xn
• Statements: 20/22-51/53
• Safety Statements: 36/37/39-61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC1NC2=NC(=C(C(=N2)N)C#N)N
• Description: Dicyclanil is an insect growth regulator belonging to the group of pyrimidinamines.Dicyclanil is a pyrimidin derivative. Dicyclanil is an insect development inhibitor very specific for the prevention of blowfly strike in sheep. It does not control any other external parasites of sheep. It is used mainly as a spray-on. It is not used in other livestock, horses or pets.
• Uses: Dicyclanil is a veterinary medication for the protection against early season myiasis.

Technology Process of Dicyclanil

There total 4 articles about Dicyclanil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

4,6-diamino-5-fluoro-2-cyclopropylaminopyrimidine + potassium ferrocyanide → 2-cyclopropylamino-4,6-diamino-5-cyanopyrimidine (112636-83-6)

Guidance literature:

In N,N-dimethyl-formamide; at 100 ℃; for 3.5h; Temperature; Large scale;

Reference yield: 68.7%

4,6-diamino-2-chloro-5-cyanopyrimidine (18340-56-2) + Cyclopropylamine (765-30-0) → 2-cyclopropylamino-4,6-diamino-5-cyanopyrimidine (112636-83-6)

Guidance literature:

With potassium hydroxide; In acetonitrile; for 5h; Reagent/catalyst; Solvent; Reflux;

Reference yield:

dimethyl N-cyanodithioiminocarbonate (10191-60-3) + Cyclopropylamine (765-30-0) + malononitrile (109-77-3) → 2-cyclopropylamino-4,6-diamino-5-cyanopyrimidine (112636-83-6)

Guidance literature:

malononitrile; With sodium methylate; In methanol; at 0 - 5 ℃; for 0.5h;

dimethyl N-cyanodithioiminocarbonate; In methanol; at 0 - 5 ℃; for 12h;

Cyclopropylamine; Further stages;

upstream raw materials:

dimethyl N-cyanodithioiminocarbonate

Cyclopropylamine

malononitrile

4,6-diamino-2-chloro-5-cyanopyrimidine

Refernces

• 1、 -. "Dicyclanil preparation method". Paragraph 0008. . Retrieved 2018/04/02.
• 2、 -. "Active agent combinations". . . Retrieved 2008/06/13.