2-nitro-1-(4-nitrophenyl)-1-heptanol

Base Information

• Chemical Name: 2-nitro-1-(4-nitrophenyl)-1-heptanol
• CAS No.: 692752-31-1
• Molecular Formula: C₁₃H₁₈N₂O₅
• Molecular Weight: 282.296
• Mol file: 692752-31-1.mol

Synonyms:2-nitro-1-(4-nitrophenyl)-1-heptanol

Chemical Property of 2-nitro-1-(4-nitrophenyl)-1-heptanol

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-nitro-1-(4-nitrophenyl)-1-heptanol

There total 3 articles about 2-nitro-1-(4-nitrophenyl)-1-heptanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

TiCl3 (OPriso) + 1-nitrohexane (646-14-0) + 4-nitrobenzaldehdye (555-16-8) + disodium ethylenediaminetetraacetic acid (64-02-8,139-33-3,150-38-9,7379-28-4,17421-79-3,71705-16-3,116229-67-5) → 2-nitro-1-(4-nitrophenyl)-1-heptanol (692752-31-1)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; dichloromethane;

Reference yield: 76.0%

1-nitrohexane (646-14-0) + 4-nitrobenzaldehdye (555-16-8) → 2-nitro-1-(4-nitrophenyl)-1-heptanol (692752-31-1)

Guidance literature:

With cetyltrimethylammonium hydroxide; at 20 ℃; for 4h;

DOI:10.1016/j.tet.2004.01.067

Reference yield:

1-nitrohexane (646-14-0) + 4-nitrobenzaldehdye (555-16-8) → 2-nitro-1-(4-nitrophenyl)-1-heptanol (692752-31-1) + 1-Nitro-4-((E)-2-nitro-hept-1-enyl)-benzene (126416-06-6)

Guidance literature:

With aluminum oxide; carbon dioxide; for 18h; Pressure; Temperature; Solvent; Reagent/catalyst; chemoselective reaction; Reactivity; Alkaline conditions;

DOI:10.1021/jo801650p

upstream raw materials:

1-nitrohexane

4-nitrobenzaldehdye

disodium ethylenediaminetetraacetic acid

Refernces

• 1、 Ballini, Roberto,Noe, Marco,Perosa, Alvise,Selva, Maurizio. "Selective nitroaldol condensations over heterogeneous catalysts in the presence of supercritical carbon dioxide". supporting information; experimental part. p. 8520 - 8528. Retrieved 2009/04/05.
• 2、 Barrett, Anthony G. M.,Robyr, Chantal,Spilling, Christopher D.. "Dichloroisopropoxytitanium Nitronates as Reagents for Stereoselective Henry Reactions". . p. 1233 - 1234. Retrieved 2007/10/02.