Bisoprolol fumarate

Base Information Edit

Chemical Name:Bisoprolol fumarate
CAS No.:105878-43-1
Molecular Formula:C₄H₄O₄*C₁₈H₃₁NO₄
Molecular Weight:441.522
Hs Code.:
NSC Number:759181
UNII:U057CX04H0
Wikidata:Q27290514
NCI Thesaurus Code:C28871
RXCUI:142146
ChEMBL ID:CHEMBL1200708
Mol file:105878-43-1.mol

Synonyms:Bisoprolol;Bisoprolol Fumarate;Bisoprolol Fumarate (1:1) Salt, (+-)-Isomer;Bisoprolol Fumarate (2:1) Salt, (+-)-Isomer;Bisoprolol Hydrochloride;Bisoprolol Methanesulfonate Salt;Bisoprolol, (+-)-Isomer;Bisoprolol, (-)-Isomer;Bisoprolol, Fumarate (1:1) Salt;Bisoprolol, Fumarate (2:1) Salt;CL 297939;CL-297939;CL297939;Concor;EMD 33512;EMD-33512;EMD33512;Fumarate, Bisoprolol;Hydrochloride, Bisoprolol

Suppliers and Price of Bisoprolol fumarate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of Bisoprolol fumarate Edit

Chemical Property:

Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:14
Exact Mass:441.23626707
Heavy Atom Count:31
Complexity:397

Purity/Quality:

Safty Information:

Pictogram(s):
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MSDS Files:

Useful:

Canonical SMILES:CC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O.C(=CC(=O)O)C(=O)O
Isomeric SMILES:CC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O.C(=C/C(=O)O)\C(=O)O
Recent ClinicalTrials:Pharmacogenetic Study of Bisoprolol in Egyptian Patients With Acute Coronary Syndrome
Recent EU Clinical Trials:A randomised, double-blind placebo controlled trial of the effectiveness of the beta-blocker bisoprolol in preventing exacerbations of chronic obstructive pulmonary disease.
Recent NIPH Clinical Trials:Phase III clinical study of TY-0201 in patients with chronic atrial fibrillation -Confirmatory Study-

Technology Process of Bisoprolol fumarate

There total 6 articles about Bisoprolol fumarate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%