Yonogenin

Base Information

• Chemical Name: Yonogenin
• CAS No.: 2460-96-0
• Molecular Formula: C₂₇H₄₄O₄
• Molecular Weight: 432.644
• Metabolomics Workbench ID: 35120
• Nikkaji Number: J7.581G
• Mol file: 2460-96-0.mol

Synonyms:Yonogenin;(25R)-5beta-spirostan-2beta,3alpha-diol;LMST01080026

Chemical Property of Yonogenin

Chemical Property:

• Vapor Pressure: 1.22E-13mmHg at 25°C
• Boiling Point: 534.2°C at 760 mmHg
• Flash Point: 276.9°C
• PSA: 58.92000
• Density: 1.16g/cm³
• LogP: 4.76460
• XLogP3: 5.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 432.32395988
• Heavy Atom Count: 31
• Complexity: 726

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CC(C(C6)O)O)C)C)C)OC1
• Isomeric SMILES: C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC[C@H]6[C@@]5(C[C@@H]([C@H](C6)O)O)C)C)C)OC1

Technology Process of Yonogenin

There total 10 articles about Yonogenin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(25R)-5β-spirost-2β,3β-diol (469-97-6) → yonogenin (2460-96-0)

Guidance literature:

With ethanol; sodium ethanolate; at 200 ℃;

DOI:10.1021/ja01201a032

Reference yield:

→ cyclopseudomarkogenin (469-96-5,469-97-6,469-98-7,511-94-4,511-96-6,562-35-6,664-82-4,2460-96-0,6811-13-8,14335-59-2,34621-07-3,61046-17-1,61046-18-2,108101-24-2,108814-76-2,108814-79-5)

Guidance literature:

With pyridine hydrochloride; acetic anhydride; Erwaermen des Reaktionsprodukts mit methanol. Kalilauge und anschliessendes Behandeln mit Essigsaeure;

DOI:10.1021/ja01626a058

Reference yield:

(25R)-5β-spirost-2-ene (16653-85-3) → (25R)-5β-Spirostan-2α,3α-diol (469-96-5,469-97-6,469-98-7,511-94-4,511-96-6,562-35-6,664-82-4,2460-96-0,6811-13-8,14335-59-2,34621-07-3,61046-17-1,61046-18-2,108101-24-2,108814-76-2,108814-79-5)

Guidance literature:

With iodine; silver(I) acetate; acetic acid; Behandeln des Reaktionsprodukts mit methanol. Kalilauge;

upstream raw materials:

ethanol

sodium ethanolate

(25R)-5β-spirost-2β,3β-diol

bis-O-methanesulfonyl-yonogenin

Downstream raw materials:

markogenin