ETHANE SULFINIC ACID SODIUM SALT

Base Information

• Chemical Name: ETHANE SULFINIC ACID SODIUM SALT
• CAS No.: 20035-08-9
• Molecular Formula: C2H5NaO2S
• Molecular Weight: 116.116
• Hs Code.: 2930909090
• Mol file: 20035-08-9.mol

Synonyms:NSC 371084;Sodium ethanesulfinate;

Chemical Property of ETHANE SULFINIC ACID SODIUM SALT

Chemical Property:

• Vapor Pressure: 0.0102mmHg at 25°C
• Melting Point: 292°C
• Refractive Index: 1.546
• Boiling Point: 244°C at 760 mmHg
• Flash Point: 101.4°C
• PSA: 59.34000
• Density: 1.372
• LogP: 0.75110
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

sodiumethanesulfinate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: The following Baran Sulfinate is a part of a toolbox of diversification reagents, which are ideal for the late-stage functionalization of nitrogen-containing heterocycles. The regioselectivity can be effectively tuned by modification of the pH and solvent selection.Radical-Based Regioselective C–H Functionalization of Electron-Deficient Heteroarenes: Scope; Tunability; and Predictability

Technology Process of ETHANE SULFINIC ACID SODIUM SALT

There total 6 articles about ETHANE SULFINIC ACID SODIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

Ethanesulfonyl chloride (594-44-5) → sodium ethanesulfinate (20035-08-9)

Guidance literature:

With sodium sulfide; sodium hydrogencarbonate; In water; at 75 - 80 ℃; for 2h;

DOI:10.1039/c3ra42932f

Reference yield:

diethylsulfone (597-35-3) + sodium ethanolate (141-52-6) → ethene (74-85-1) + sodium ethanesulfinate (20035-08-9)

Guidance literature:

With ethanol; at 235 ℃;

Reference yield:

1-methyl-4-nitrosobenzene (623-11-0) + ethanesulfonylmethyl-trimethyl-ammonium; chloride (115050-45-8) → sodium ethanesulfinate (20035-08-9) + trimethylamine (75-50-3)

Guidance literature:

DOI:10.1002/ardp.19542870909

upstream raw materials:

diethylsulfone

sodium ethanolate

1-methyl-4-nitrosobenzene

ethanesulfonylmethyl-trimethyl-ammonium; chloride

Downstream raw materials:

2-ethanesulfonylmethyl-pyridine

[2-(ethanesulfonyl)ethyl](methyl)amine

1-Ethylsulfonyl-4,4-bis-<4-N,N-dimethylamino-phenyl>-1,2-dicyan-butadien-(1,3)

Ethanesulfonyl-(2-phenoxy-ethoxycarbonylamino)-acetic acid

Refernces

• 1、 Chen, Guang-Le,He, Shi-Hui,Cheng, Liang,Liu, Feng. "Copper-Catalyzed N-Directed Distal C(sp3)-H Sulfonylation and Thiolation with Sulfinate Salts". supporting information. p. 8338 - 8342. Retrieved 2021/10/25.
• 2、 -. "Preparation method of substituted sulfinate". Paragraph 0023-0029. . Retrieved 2020/12/30.