EPO

Base Information

• Chemical Name: EPO
• CAS No.: 11096-26-7
• Molecular Formula: Unspecified
• Molecular Weight: 461.00098
• Hs Code.: 3504009000
• Mol file: 11096-26-7.mol

Synonyms:EPO;Epocim;Epocrin;Epoetin;Epogis S;Eposim;Erytrostim;Heberitro;Hemax;Hempoietine;Repotin;YiBei;

Chemical Property of EPO

Chemical Property:

• Appearance/Colour: lyophilized powder
• PSA: 0.00000
• LogP: 0.00000
• Storage Temp.: −20°C

Purity/Quality:

99% ^*data from raw suppliers

Erythropoietin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Biological functions: As a primary target of EPO for erythropoiesis, EPOR is expressed in the organs of hematopoiesis, including the fetal liver as well as the adult bone marrow and spleen. EPO-EPOR signaling regulates the proliferation/differentiation and survival of the erythroid progenitors, providing an important stage-specific function of erythroid differentiation. The numbers of EPOR expressed in various cells are relatively low and range between 100 and 3000 per cell with the binding affinity (ED50) to EPO ranging from 0.1–3 nM. A wide distribution of EPOR expression is confirmed on renal cells, endothelial cells, cardiomyocytes, the brain, and peripheral nervous system where EPO may exert pleiotropic or antiapoptotic effects.
• Description: Recombinant erythropoietin (EPO) is currently indicated for use only in anemia associated with renal transplant or end-stage renal disease. Widened indications for use in other forms of anemia, accompanied by price reductions as a result of keen competition, have been projected for EPO in the future.
• Uses: Erythropoietin can be used in biological study of its attenuation of cardiac dysfunction in rats by inhibiting endoplasmic reticulum stress-induced diabetic cardiomyopathy.