diphenylmethanone O-(adamantane-1-carbonyl) oxime

Base Information

• Chemical Name: diphenylmethanone O-(adamantane-1-carbonyl) oxime
• CAS No.: 107264-20-0
• Molecular Formula: C₂₄H₂₅NO₂
• Molecular Weight: 359.468
• Mol file: 107264-20-0.mol

Synonyms:diphenylmethanone O-(adamantane-1-carbonyl) oxime

Chemical Property of diphenylmethanone O-(adamantane-1-carbonyl) oxime

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of diphenylmethanone O-(adamantane-1-carbonyl) oxime

There total 4 articles about diphenylmethanone O-(adamantane-1-carbonyl) oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

Benzophenone oxime (574-66-3) + adamantane-2-carboxylic acid (15897-81-1) → diphenylmethanone O-(adamantane-1-carbonyl) oxime (107264-20-0)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; Schlenk technique; Inert atmosphere;

DOI:10.1002/anie.201912907

Reference yield:

benzophenone (119-61-9) → diphenylmethanone O-(adamantane-1-carbonyl) oxime (107264-20-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium acetate; hydroxylamine hydrochloride / water; ethanol / 80 °C / Schlenk technique; Inert atmosphere

2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C / Schlenk technique; Inert atmosphere

With dmap; hydroxylamine hydrochloride; sodium acetate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In ethanol; dichloromethane; water;

DOI:10.1002/anie.201912907

Reference yield:

Benzophenone oxime (574-66-3) + 1-Adamantanecarboxylic acid (828-51-3) → diphenylmethanone O-(adamantane-1-carbonyl) oxime (107264-20-0)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane;

DOI:10.1016/S0040-4039(00)84763-2

upstream raw materials:

Benzophenone oxime

1-Adamantanecarboxylic acid

1-Adamantanecarbonyl chloride

adamantane-2-carboxylic acid

Downstream raw materials:

benzophenone

1-phenyladamantane

benzophenone azine

adamantane

Refernces

• 1、 Hasebe, Masato,Tsuchiya, Takashi. "PHOTOCHEMICAL GENERATION OF ALIPHATIC RADICALS FROM BENZOPHENONE OXIME ESTERS: SIMPLE SYNTHESIS OF ALKYLBENZENES AND ALKYLPYRIDINES". . p. 3239 - 3242. Retrieved 2007/10/02.