Diphenylmethane-4,4'-disulfonamide

Base Information

• Chemical Name: Diphenylmethane-4,4'-disulfonamide
• CAS No.: 535-66-0
• Molecular Formula: C13H14 N2 O4 S2
• Molecular Weight: 326.39
• UNII: 3XX3D53Z2M
• DSSTox Substance ID: DTXSID00968232
• Nikkaji Number: J39.678H
• Wikidata: Q27258196
• Mol file: 535-66-0.mol

Synonyms:Liowas;Diphenylmethane-4,4'-disulfonamide;Diurodin;Nirexon;Polidral;535-66-0;Bis(p-sulfamoylphenyl)methane;4,4'-Methylenebis(benzenesulfonamide);3XX3D53Z2M;4-[(4-sulfamoylphenyl)methyl]benzenesulfonamide;UNII-3XX3D53Z2M;Benzenesulfonamide, 4,4'-meethylenebis-;CBDivE_011091;SCHEMBL309694;Diphenylmethan-4,4'-disulfonamid;DTXSID00968232;Benzenesulfonamide, 4,4'-methylenebis-;4,4'-Methylenedi(benzene-1-sulfonamide);SR-01000199756;SR-01000199756-1;Q27258196

Chemical Property of Diphenylmethane-4,4'-disulfonamide

Chemical Property:

• Melting Point: 178-180 °C
• Boiling Point: 576°Cat760mmHg
• PKA: 9.81±0.10(Predicted)
• Flash Point: 302.1°C
• PSA: 137.08000
• Density: 1.439g/cm³
• LogP: 4.13440
• XLogP3: 1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 326.03949928
• Heavy Atom Count: 21
• Complexity: 482

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1CC2=CC=C(C=C2)S(=O)(=O)N)S(=O)(=O)N

Technology Process of Diphenylmethane-4,4'-disulfonamide

There total 3 articles about Diphenylmethane-4,4'-disulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

diphenylmethane-4,4'-disulfonyl chloride (3119-64-0) → diphenylmethane-4,4'-disulfonamide (535-66-0)

Guidance literature:

With ammonia; In methanol; for 3h;

Reference yield:

Diphenylmethane (101-81-5) → diphenylmethane-4,4'-disulfonamide (535-66-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / ClSO₃H / 48 h

2: 37 percent / NH₃ / methanol / 3 h

With chlorosulfonic acid; ammonia; In methanol;

Reference yield:

→ diphenylmethane-4,4'-disulfonamide (535-66-0)

Guidance literature:

upstream raw materials:

diphenylmethane-4,4'-disulfonyl chloride

Diphenylmethane

Downstream raw materials:

4,4'-methylenebis[N-(2,2,2-trichloro-1-hydroxyethyl)benzenesulfonamide]

4,4'-methylenebis(N,N-dichlorobenzenesulfonamide)

benzophenone-4,4'-disulfonamide

Refernces

• 1、 -. "Oxyformamidates". . . Retrieved 2008/06/13.