(E)-4-bromo-2-nitro-β-piperidinostyrene

Base Information

• Chemical Name: (E)-4-bromo-2-nitro-β-piperidinostyrene
• CAS No.: 108061-73-0
• Molecular Formula: C₁₃H₁₅BrN₂O₂
• Molecular Weight: 311.178
• Mol file: 108061-73-0.mol

Synonyms:(E)-4-bromo-2-nitro-β-piperidinostyrene

Chemical Property of (E)-4-bromo-2-nitro-β-piperidinostyrene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (E)-4-bromo-2-nitro-β-piperidinostyrene

There total 2 articles about (E)-4-bromo-2-nitro-β-piperidinostyrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Methyl-3-nitroanilin (119-32-4) → (E)-4-bromo-2-nitro-β-piperidinostyrene (108061-73-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) sodium nitrite, 16percent HBr, 2.) copper(I) bromide / 1.) water, -1 deg C, 2.) water, 70 deg C, 1 h

2: 4 h / 110 °C

With hydrogen bromide; copper(I) bromide; sodium nitrite;

DOI:10.1021/ja00245a031

Reference yield:

tris(piperidino)-methane (22630-08-6) + 4-bromo-2-nitrotoluene (60956-26-5) → (E)-4-bromo-2-nitro-β-piperidinostyrene (108061-73-0)

Guidance literature:

at 110 ℃; for 4h;

DOI:10.1021/ja00245a031

Reference yield:

(E)-4-bromo-2-nitro-β-piperidinostyrene (108061-73-0) → 6-bromo-1H-indole (52415-29-9)

Guidance literature:

With titanium(III) chloride; ammonium acetate buffer; In water; acetone; for 0.166667h; Yield given;

DOI:10.1021/ja00245a031

upstream raw materials:

tris(piperidino)-methane

4-bromo-2-nitrotoluene

4-Methyl-3-nitroanilin

Downstream raw materials:

6-bromo-1H-indole