3-{[(4-methylphenyl)sulfonyl]oxy}-2-({[(4-methylphenyl)sulfonyl]oxy}methyl)-2-phenylpropyl 4-methylbenzenesulfonate

Base Information

• Chemical Name: 3-{[(4-methylphenyl)sulfonyl]oxy}-2-({[(4-methylphenyl)sulfonyl]oxy}methyl)-2-phenylpropyl 4-methylbenzenesulfonate
• CAS No.: 162463-14-1
• Molecular Formula: C₃₁H₃₂O₉S₃
• Molecular Weight: 644.788
• Mol file: 162463-14-1.mol

Synonyms:α,α,α-tris<(4-tolylsulfonyl)methyl>toluene

Chemical Property of 3-{[(4-methylphenyl)sulfonyl]oxy}-2-({[(4-methylphenyl)sulfonyl]oxy}methyl)-2-phenylpropyl 4-methylbenzenesulfonate

Chemical Property:

Purity/Quality:

[3-(4-METHYLPHENYL)SULFONYLOXY-2-[(4-METHYLPHENYL)SULFONYLOXYMETHYL]-2-PHENYLPROPYL] 4-METHYLBENZENESULFONATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-{[(4-methylphenyl)sulfonyl]oxy}-2-({[(4-methylphenyl)sulfonyl]oxy}methyl)-2-phenylpropyl 4-methylbenzenesulfonate

There total 3 articles about 3-{[(4-methylphenyl)sulfonyl]oxy}-2-({[(4-methylphenyl)sulfonyl]oxy}methyl)-2-phenylpropyl 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

α,α,α-tris(hydroxymethyl)toluene (4704-99-8) + p-toluenesulfonyl chloride (98-59-9) → α,α,α-tris<(4-tolylsulfonyl)methyl>toluene (162463-14-1)

Guidance literature:

With pyridine; for 16h; Ambient temperature;

Reference yield:

phenylacetaldehyde (122-78-1) → α,α,α-tris<(4-tolylsulfonyl)methyl>toluene (162463-14-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 25 percent / calcium hydroxide / tetrahydrofuran / 120 h / 60 - 65 °C

2: 82 percent / pyridine / 4 - 30 °C

With pyridine; calcium hydroxide; In tetrahydrofuran;

DOI:10.1016/j.tet.2007.05.022

Reference yield:

phenylacetaldehyde (122-78-1) → α,α,α-tris<(4-tolylsulfonyl)methyl>toluene (162463-14-1)

Guidance literature:

Multi-step reaction with 2 steps

1: Ca(OH)2 / tetrahydrofuran / Heating

2: pyridine

With calcium hydroxide; In tetrahydrofuran; pyridine;

DOI:10.1002/1099-0682(200107)2001:7<1789::AID-EJIC1789>3.0.CO;2-C

upstream raw materials:

α,α,α-tris(hydroxymethyl)toluene

p-toluenesulfonyl chloride

phenylacetaldehyde

Downstream raw materials:

α,α,α-tris(azidomethyl)toluene

α,α,α-tris[((triphenylphosphoranylidene)amino)methyl]toluene

α,α,α-tris[((tricyclopentylphosphoranylidene)amino)methyl]toluene

α,α,α-tris(aminomethyl)toluene

Refernces

• 1、 Viguier, Romain,Serratrice, Guy,Dupraz, Agnes,Dupuy, Claude. "New polypodal polycarboxylic ligands - Complexation of rare-earth ions in aqueous solution". . p. 1789 - 1795. Retrieved 2007/10/03.