ethyl 4-methyl-3-oxo-2-phenylpentanoate

Base Information

• Chemical Name: ethyl 4-methyl-3-oxo-2-phenylpentanoate
• CAS No.: 32039-90-0
• Molecular Formula: C₁₄H₁₈O₃
• Molecular Weight: 234.295
• Mol file: 32039-90-0.mol

Synonyms:ethyl 4-methyl-3-oxo-2-phenylpentanoate

Chemical Property of ethyl 4-methyl-3-oxo-2-phenylpentanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 4-methyl-3-oxo-2-phenylpentanoate

There total 6 articles about ethyl 4-methyl-3-oxo-2-phenylpentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Methyl-3-oxo-2-phenyl-pentanimidic acid ethyl ester → ethyl 4-methyl-3-oxo-2-phenylpentanoate (32039-90-0)

Guidance literature:

With hydrogenchloride; In ethanol; at 40 ℃; Yield given;

DOI:10.1248/cpb.38.2726

Reference yield:

C14H18O3 → ethyl 4-methyl-3-oxo-2-phenylpentanoate (32039-90-0)

Guidance literature:

With dmap; In 1,4-dioxane; at 100 ℃; for 3h;

DOI:10.1021/acs.joc.8b02715

Reference yield:

4-methyl-3-oxo-2-phenyl-pentanenitrile (32039-89-7) → ethyl 4-methyl-3-oxo-2-phenylpentanoate (32039-90-0)

Guidance literature:

With hydrogenchloride; ethanol; Erwaermen des erhaltenen Iminoaether-hydrochlorids mit verd. Alkohol;

upstream raw materials:

4-methyl-3-oxo-2-phenyl-pentanenitrile

phenylacetonitrile

ethoxyethynylbenzene

Downstream raw materials:

3-methyl-1-phenylbutan-2-one

6-Isopropyl-5-phenyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one

phenylacetic acid

isobutyric Acid

Refernces

• 1、 Watanabe,Usui,Shibano,Tanaka,Kanao. "Syntheses of monocyclic and bicyclic 2,4(1H,3H)-pyrimidinediones and their serotonin 2 antagonist activities". . p. 2726 - 2732. Retrieved 2007/10/02.