ethanone-1-phenyl-O-(phenylmethyl)oxime

Base Information

• Chemical Name: ethanone-1-phenyl-O-(phenylmethyl)oxime
• CAS No.: 28570-76-5
• Molecular Formula: C₁₅H₁₅NO
• Molecular Weight: 225.29
• Mol file: 28570-76-5.mol

Synonyms:ethanone-1-phenyl-O-(phenylmethyl)oxime

Chemical Property of ethanone-1-phenyl-O-(phenylmethyl)oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethanone-1-phenyl-O-(phenylmethyl)oxime

There total 15 articles about ethanone-1-phenyl-O-(phenylmethyl)oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzyl chloride (100-44-7) + acetophenone (98-86-2) → ethanone-1-phenyl-O-(phenylmethyl)oxime (28570-76-5)

Guidance literature:

With potassium hydroxide; hydroxylamine hydrochloride; In water; dimethyl sulfoxide; for 0.5h;

DOI:10.1081/SCC-120015807

Reference yield: 94.0%

O-benzylhydoxylamine hydrochloride (2687-43-6) + acetophenone (98-86-2) → ethanone-1-phenyl-O-(phenylmethyl)oxime (28570-76-5)

Guidance literature:

With sulfuric acid; In ethanol; for 10h; Heating;

Reference yield: 90.0%

(E)-1-phenylethanone oxime (10341-75-0) + benzyl bromide (100-39-0) → (E)-ethanone-1-phenyl-O-(phenylmethyl)oxime (28570-76-5,106770-94-9)

Guidance literature:

With potassium hydroxide; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

DOI:10.1021/np300648d

upstream raw materials:

acetophenone oxime

benzyl chloride

O-benzylhydoxylamine hydrochloride

acetophenone

Downstream raw materials:

(S)-1-phenyl-ethylamine

(R)-1-phenyl-ethyl-amine

O-benzyl-N-(1-phenylethyl)hydroxylamine

(1S)-N-1-Phenethyl-3-hydroxy-2,2-dimethylpropanamide

Refernces

• 1、 Zhang, Xiao,Rovis, Tomislav. "Photocatalyzed Triplet Sensitization of Oximes Using Visible Light Provides a Route to Nonclassical Beckmann Rearrangement Products". supporting information. p. 21211 - 21217. Retrieved 2021/12/27.
• 2、 Ma, Cong,Zhao, Chuan-Qi,Li, Yi-Qian,Zhang, Li-Pu,Xu, Xue-Tao,Zhang, Kun,Mei, Tian-Sheng. "Palladium-catalyzed C-H activation/C-C cross-coupling reactions: Via electrochemistry". . p. 12189 - 12192. Retrieved 2017/11/16.