Spiro[3.4]octane

Base Information

• Chemical Name: Spiro[3.4]octane
• CAS No.: 175-56-4
• Molecular Formula: C8H14
• Molecular Weight: 110.2
• Hs Code.: 2902199090
• Mol file: 175-56-4.mol

Synonyms:

Chemical Property of Spiro[3.4]octane

Chemical Property:

• Vapor Pressure: 5.55mmHg at 25°C
• Boiling Point: 147.6°C at 760 mmHg
• Flash Point: 23.3°C
• PSA: 0.00000
• Density: 0.89g/cm³
• LogP: 2.73070

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Spiro[3.4]octane

There total 11 articles about Spiro[3.4]octane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Spiro<3.4>octa-5,7-dien (15439-15-3) → spiro[3.4]octane (175-56-4)

Guidance literature:

With hydrogen; platinum(IV) oxide; In hexane;

DOI:10.1021/ja00806a056

Reference yield:

2,2'-(cyclobutane-1,1-diyl)diacetonitrile (1073-90-1) → spiro[3.4]octane (175-56-4)

Guidance literature:

Multi-step reaction with 8 steps

1: (i) aq. HCl, (ii) /BRN= 1718733/

2: Na / toluene

3: aq. HCl / tetrahydrofuran

4: (i) TsCl, Py, (ii) LiCl, acetone

5: Li₂CO₃, LiBr / dimethylformamide

6: DIBAH / benzene

7: (i) Ph₃P, CCl₄, (ii) KOtBu, triglyme

8: H₂ / PtO₂ / hexane

With hydrogenchloride; hydrogen; sodium; lithium carbonate; diisobutylaluminium hydride; lithium bromide; platinum(IV) oxide; In tetrahydrofuran; hexane; N,N-dimethyl-formamide; toluene; benzene;

DOI:10.1021/ja00806a056

Reference yield:

Spiro[3.4]oct-7-en-6-ol (50782-05-3) → spiro[3.4]octane (175-56-4)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) Ph₃P, CCl₄, (ii) KOtBu, triglyme

2: H₂ / PtO₂ / hexane

With hydrogen; platinum(IV) oxide; In hexane;

DOI:10.1021/ja00806a056

upstream raw materials:

Spiro<3.4>octa-5,7-dien

spiro[3.4]octan-5-one

2,2'-(cyclobutane-1,1-diyl)diacetonitrile

Spiro[3.4]oct-7-en-6-ol

Refernces