Multi-step reaction with 8 steps
1: 1.) AlCl3, 2.) 28percent NH4OH / 1.) CS2, r.t., overnight, 2.) EtOH, r.t., 72 h
2: 75 percent / HCl / 24 h / Heating
3: mCPBA / CH2Cl2 / 18 h / Heating
4: 10percent KOH / ethanol / Ambient temperature
5: 90 percent / HOBT, DCCI / dimethylformamide / 1.) 0 deg C, 2 h, 2.) r.t., 18 h
6: 1.) BH3*SMe2, 2.) MeOH / 1.) THF, reflux, 6 h, 2.) r.t., 12 h
7: 90 percent / formamide / 1 h / Heating
8: 92 percent / NaH / dimethylformamide / 1.) 30 min, 2.) 60 deg C, 3 h
With
hydrogenchloride; methanol; potassium hydroxide; ammonium hydroxide; aluminium trichloride; dimethylsulfide borane complex; sodium hydride; benzotriazol-1-ol; 3-chloro-benzenecarboperoxoic acid; dicyclohexyl-carbodiimide;
In
ethanol; dichloromethane; formamide; N,N-dimethyl-formamide;