9,10-Didehydro-6-methyl-8-hydroxymethylergoline

Base Information Edit

Chemical Name:9,10-Didehydro-6-methyl-8-hydroxymethylergoline
CAS No.:602-85-7
Molecular Formula:C16H18N2O
Molecular Weight:254.332
Hs Code.:
European Community (EC) Number:210-024-5
Nikkaji Number:J2.673.613G
Wikipedia:Lysergol
ChEMBL ID:CHEMBL1895462
Mol file:602-85-7.mol

Synonyms:Lysergole;NSC 196867;9,10-Didehydro-6-methyl-8-hydroxymethylergoline;Ergoline, 9,10-didehydro-8-hydroxymethyl-6-methyl-;LOL;EINECS 210-024-5;BRN 0088476;9,10-Didehydro-6-methylergoline-8beta-methanol;602-85-7;4-23-00-02717 (Beilstein Handbook Reference);Ergoline-8beta-methanol, 9,10-didehydro-6-methyl-;CHEMBL1895462;Ergoline-8-methanol, 9,10-didehydro-6-methyl-, (8beta)-;Ergoline-8-methanol, 9,10-didehydro-6-methyl-, (8-beta)-;CCG-208329

Suppliers and Price of 9,10-Didehydro-6-methyl-8-hydroxymethylergoline

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Lysergol
2.5g
$ 1065.00

Medical Isotopes, Inc.
Lysergol
100 mg
$ 650.00

Medical Isotopes, Inc.
Lysergol
1 g
$ 2200.00

Biorbyt Ltd
Lysergol
100 mg
$ 472.60

Biorbyt Ltd
Lysergol
20 mg
$ 289.00

American Custom Chemicals Corporation
LYSERGOL 95.00%
5MG
$ 499.59

AK Scientific
Lysergol
1g
$ 635.00

AK Scientific
Lysergol
25mg
$ 103.00

AHH
Lysergol 97%
10g
$ 318.00

Total 90 raw suppliers

Chemical Property of 9,10-Didehydro-6-methyl-8-hydroxymethylergoline Edit

Chemical Property:

Appearance/Colour:Off-white to beige crystalline powder
Melting Point:248°C
Refractive Index:1.6240 (estimate)
Boiling Point:465.8 °C at 760 mmHg
PKA:14.61±0.10(Predicted)
Flash Point:235.5 °C
PSA：39.26000
Density:1.3 g/cm³
LogP:1.96780
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:254.141913202
Heavy Atom Count:19
Complexity:394

Purity/Quality:

≥95% ^*data from raw suppliers

Lysergol ^*data from reagent suppliers

Safty Information:

Pictogram(s): T+
Hazard Codes:T+,T
Statements: 26/27/28-36/37/38-25
Safety Statements: 26-36/37/39-45-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CC(C=C2C1CC3=CNC4=CC=CC2=C34)CO
Isomeric SMILES:CN1C[C@H](C=C2[C@@H]1CC3=CNC4=CC=CC2=C34)CO
Description Lysergol?is an?alkaloid?of the?ergoline?family that occurs as a minor constituent in some species of?fungi?(most within?Claviceps), and in the morning glory family of plants (Convolvulaceae), including the?hallucinogenic?seeds of?Rivea corymbosa?(ololiuhqui),?Argyreia nervosa?(Hawaiian baby woodrose) and?Ipomoea violacea. Lysergol is not a controlled substance in the USA. Its possession and sale is also legal under the U.S.?Federal Analog Act?because it does not have a known pharmacological action or a precursor relationship to?LSD, which is a controlled substance. However, lysergol is an intermediate in the manufacture of some ergoloid medicines (e.g.,?nicergoline).
Uses Lysergol is an ergot alkaloid which when used in combination with antibiotic nalidixic acid, can effectively inhibit Escherichia coli. It also maintains the potential to act on the 5-HT1/2 receptors and at α1-adrenergic receptors thus acting as a neuropsychiatric drug.

Technology Process of 9,10-Didehydro-6-methyl-8-hydroxymethylergoline

There total 20 articles about 9,10-Didehydro-6-methyl-8-hydroxymethylergoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%