C₂₇H₃₂N₆O₄S

Base Information

• Chemical Name: C₂₇H₃₂N₆O₄S
• CAS No.: 1007310-62-4
• Molecular Formula: C₂₇H₃₂N₆O₄S
• Molecular Weight: 536.655
• Mol file: 1007310-62-4.mol

Synonyms:C₂₇H₃₂N₆O₄S

Chemical Property of C₂₇H₃₂N₆O₄S

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₇H₃₂N₆O₄S

There total 5 articles about C₂₇H₃₂N₆O₄S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

4-phenyl-1-piperazine (92-54-6) + 5-(5-Chlorosulphonyl-2-ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one (139756-22-2) → C27H32N6O4S (1007310-62-4)

Guidance literature:

With triethylamine; In ethanol; at 30 ℃; for 0.0833333h; microwave irradiation;

DOI:10.1021/jm701400r

Reference yield:

5-(2-ethoxy)-phenyl-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidine-7-one (139756-21-1) → C27H32N6O4S (1007310-62-4)

Guidance literature:

Multi-step reaction with 2 steps

1: chlorosulfonic acid / chloroform / 0.17 h / 25 °C / Flow reactor

2: chloroform / 0.08 h / 25 °C / Flow reactor

With chlorosulfonic acid; In chloroform;

DOI:10.1039/d1ra08220e

Reference yield:

2-ethoxylbenzaldehyde (613-69-4) → C27H32N6O4S (1007310-62-4)

Guidance literature:

Multi-step reaction with 3 steps

1: sulphonated graphene oxide / chloroform / 0.27 h / 120 °C / 12751.3 Torr / Flow reactor

2: chlorosulfonic acid / chloroform / 0.17 h / 25 °C / Flow reactor

3: chloroform / 0.08 h / 25 °C / Flow reactor

With chlorosulfonic acid; In chloroform;

DOI:10.1039/d1ra08220e

upstream raw materials:

4-phenyl-1-piperazine

5-(5-Chlorosulphonyl-2-ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

2-ethoxylbenzaldehyde

5-(2-ethoxy)-phenyl-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidine-7-one

Refernces

• 1、 Flores Toque, Haroldo A.,Priviero, Fernanda B. M.,Teixeira, Cleber E.,Perissutti, Elisa,Fiorino, Ferdinando,Severino, Beatrice,Frecentese, Francesco,Lorenzetti, Raquel,Baracat, Juliana S.,Santagada, Vincenzo,Caliendo, Giuseppe,Antunes, Edson,De Nucci, Gilberto. "Synthesis and pharmacological evaluations of sildenafil analogues for treatment of erectile dysfunction". . p. 2807 - 2815. Retrieved 2008/12/22.