Technology Process of 2-p-Tolyl-1H-benzoimidazole-4-carboxylic acid
There total 6 articles about 2-p-Tolyl-1H-benzoimidazole-4-carboxylic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: H2, aq. NaOH / Pd/C
2: cupric acetate, AcOH / H2O; methanol / Heating
With
sodium hydroxide; hydrogen; copper diacetate; acetic acid;
palladium on activated charcoal;
In
methanol; water;
DOI:10.1021/jm00164a054
- Guidance literature:
-
Multi-step reaction with 3 steps
1: aq. KOH / Heating
2: H2, aq. NaOH / Pd/C
3: cupric acetate, AcOH / H2O; methanol / Heating
With
potassium hydroxide; sodium hydroxide; hydrogen; copper diacetate; acetic acid;
palladium on activated charcoal;
In
methanol; water;
DOI:10.1021/jm00164a054
- Guidance literature:
-
Multi-step reaction with 6 steps
1: SOCl2 / 1 h / Heating
2: aq. NaN3 / acetone / 1 h / below 25 deg C
3: aq. AcOH / 0.17 h / Heating
4: aq. KOH / Heating
5: H2, aq. NaOH / Pd/C
6: cupric acetate, AcOH / H2O; methanol / Heating
With
potassium hydroxide; sodium hydroxide; thionyl chloride; sodium azide; hydrogen; copper diacetate; acetic acid;
palladium on activated charcoal;
In
methanol; water; acetone;
DOI:10.1021/jm00164a054
