Technology Process of 5,6-bis(4-methoxyphenyl)-3a,4,7,7a-tetrahydroisobenzofuran-1,3-dione
There total 2 articles about 5,6-bis(4-methoxyphenyl)-3a,4,7,7a-tetrahydroisobenzofuran-1,3-dione which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
toluene;
for 6h;
Heating / reflux;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: palladium diacetate; lithium tert-butoxide; oxygen; p-benzoquinone / dimethyl sulfoxide / 14 h / 90 °C / 760.05 Torr / Molecular sieve
2: zinc dibromide / acetonitrile / 18 h / 65 °C
With
oxygen; palladium diacetate; p-benzoquinone; zinc dibromide; lithium tert-butoxide;
In
dimethyl sulfoxide; acetonitrile;
2: |Diels-Alder Cycloaddition;
DOI:10.1039/c3cc43593h
- Guidance literature:
-
5,6-bis(4-methoxyphenyl)-3a,4,7,7a-tetrahydroisobenzofuran-1,3-dione;
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 25 ℃;
for 16h;
With
hydrogenchloride;
In
methanol; water;