1-Amino-2-methyl-2-propanethiol hydrochloride

Base Information

• Chemical Name: 1-Amino-2-methyl-2-propanethiol hydrochloride
• CAS No.: 32047-53-3
• Molecular Formula: C4H12ClNS
• Molecular Weight: 141.665
• Hs Code.: 2930909090
• European Community (EC) Number: 434-480-1,608-695-8
• DSSTox Substance ID: DTXSID10953917
• NSC Number: 254029
• Mol file: 32047-53-3.mol

Synonyms:32047-53-3;1-amino-2-methylpropane-2-thiol hydrochloride;1-Amino-2-methyl-2-propanethiol hydrochloride;DIMETHYLCYSTEAMINE HYDROCHLORIDE;1-amino-2-methylpropane-2-thiol;hydrochloride;EC 434-480-1;NSC 254029;2-Propanethiol, 1-amino-2-methyl-, hydrochloride;Dimethylcysteamine HCl;2-Methyl-2-thiopropylamine Hydrochloride;SCHEMBL1880943;DTXSID10953917;YZCAFAKJYGDMSY-UHFFFAOYSA-N;BCP10543;MFCD00191744;NSC254029;1-Amino-2-methyl-2-propanethiol HCl;AKOS005137923;GS-0908;NSC-254029;SB75661;1-amino-2-methylpropan2-thiol hydrochloride;CS-0140693;FT-0601930;1-amino-2-methyl-2-propanethiol hydro-chloride;2-mercapto-2-methyl-1-propylamine hydrochloride;A857478;J-520369;1-Amino-2-methyl-2-propanethiol hydrochloride, 97%;1-Amino-2-methylpropane-2-thiol--hydrogen chloride (1/1)

Chemical Property of 1-Amino-2-methyl-2-propanethiol hydrochloride

Chemical Property:

• Vapor Pressure: 0.472mmHg at 25°C
• Melting Point: 202-203 °C
• Boiling Point: 189.9 °C at 760 mmHg
• Flash Point: 68.7 °C
• PSA: 64.82000
• Density: 0.936 g/cm3
• LogP: 2.15580
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility.: Water (Slightly)
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 141.0378983
• Heavy Atom Count: 7
• Complexity: 42.8

Purity/Quality:

99% ^*data from raw suppliers

2-Methyl-2-thiopropylamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(CN)S.Cl
• Uses: 2-Methyl-2-thiopropylamine Hydrochloride is used in the synthesis of biologically oriented organic sulfur compounds.

Technology Process of 1-Amino-2-methyl-2-propanethiol hydrochloride

There total 1 articles about 1-Amino-2-methyl-2-propanethiol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

rac-2-isopropyl-5,5-dimethyl-1,3-thiazolidine → 1-amino-2-methylpropane-2-thiol hydrochloride (32047-53-3) + isobutyraldehyde (78-84-2)

Guidance literature:

With hydrogenchloride; In water; Reflux; Large scale;

Reference yield: 95.0%

1-amino-2-methylpropane-2-thiol hydrochloride (32047-53-3) + pleuromutilin → 14-O-[(1-amino-2-methylpropane-2-yl)thioacetyl]mutilin (133787-61-8)

Guidance literature:

With 2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine; benzyltri(n-butyl)ammonium chloride; In tert-butyl methyl ether; at 50 ℃; for 1h; Solvent; Reagent/catalyst; Temperature; Inert atmosphere;

Reference yield: 91.0%

phthalic anhydride (85-44-9) + 1-amino-2-methylpropane-2-thiol hydrochloride (32047-53-3) → 2-(N-(2-Methyl-2-sulfanylpropyl)carbamoyl)benzoic acid (618112-95-1)

Guidance literature:

With triethylamine; In dichloromethane;

Downstream raw materials:

5-Oxo-2,2-dimethyl-tetrahydro-thiazolo<2,3-a>isoindol

2-(2-Mercapto-ethylsulfanyl)-N-(2-mercapto-2-methyl-propyl)-2-phenyl-acetamide

2-(N-(2-Methyl-2-sulfanylpropyl)carbamoyl)benzoic acid

2-Methyl-2((2,4,6-trimethoxyphenyl)methylthio)propylamine

Refernces