Technology Process of tert-butyl N-[[5-(benzenesulfonyl)pyrimidin-2-yl]methyl]carbamate
There total 4 articles about tert-butyl N-[[5-(benzenesulfonyl)pyrimidin-2-yl]methyl]carbamate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
3-chloro-benzenecarboperoxoic acid;
In
chloroform;
at 20 ℃;
for 1h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: caesium carbonate / 1-methyl-pyrrolidin-2-one / 2 h / 100 °C
2: ammonium hydroxide; hydrogen / methanol; water / 4 h / 20 °C / 760.05 Torr
3: triethylamine / dichloromethane / 2.25 h / 20 °C
4: 3-chloro-benzenecarboperoxoic acid / chloroform / 1 h / 20 °C
With
ammonium hydroxide; hydrogen; caesium carbonate; triethylamine; 3-chloro-benzenecarboperoxoic acid;
In
1-methyl-pyrrolidin-2-one; methanol; dichloromethane; chloroform; water;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: ammonium hydroxide; hydrogen / methanol; water / 4 h / 20 °C / 760.05 Torr
2: triethylamine / dichloromethane / 2.25 h / 20 °C
3: 3-chloro-benzenecarboperoxoic acid / chloroform / 1 h / 20 °C
With
ammonium hydroxide; hydrogen; triethylamine; 3-chloro-benzenecarboperoxoic acid;
In
methanol; dichloromethane; chloroform; water;