Technology Process of C27H28O5
There total 12 articles about C27H28O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
(trimethyl-λ5-phosphanyliden)acetonitrile;
In
dichloromethane;
at 40 ℃;
for 24h;
regioselective reaction;
DOI:10.1016/j.tetlet.2011.03.154
- Guidance literature:
-
Multi-step reaction with 4 steps
1: Dess-Martin periodane / dichloromethane / 15 h / 20 °C
2: tetrahydrofuran; diethyl ether / 1 h / 0 °C
3: tetrabutyl ammonium fluoride / tetrahydrofuran / 21 h / 0 °C
4: (trimethyl-λ5-phosphanyliden)acetonitrile / dichloromethane / 24 h / 40 °C
With
tetrabutyl ammonium fluoride; Dess-Martin periodane; (trimethyl-λ5-phosphanyliden)acetonitrile;
In
tetrahydrofuran; diethyl ether; dichloromethane;
1: Dess-Martin oxidation / 4: Mitsunobu reaction;
DOI:10.1016/j.tetlet.2011.03.154
- Guidance literature:
-
Multi-step reaction with 9 steps
1.1: Dess-Martin periodane / dichloromethane / 26 h / 20 °C
2.1: tetrahydrofuran / 3 h / 0 °C
3.1: Dess-Martin periodane / dichloromethane / 15 h / 20 °C
4.1: tetrahydrofuran; toluene / 5 h / -40 °C
5.1: 9-bora-bicyclo[3.3.1]nonane / tetrahydrofuran / 5 h / 0 - 20 °C
5.2: 2 h
6.1: Dess-Martin periodane / dichloromethane / 15 h / 20 °C
7.1: tetrahydrofuran; diethyl ether / 1 h / 0 °C
8.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 21 h / 0 °C
9.1: (trimethyl-λ5-phosphanyliden)acetonitrile / dichloromethane / 24 h / 40 °C
With
tetrabutyl ammonium fluoride; Dess-Martin periodane; 9-bora-bicyclo[3.3.1]nonane; (trimethyl-λ5-phosphanyliden)acetonitrile;
In
tetrahydrofuran; diethyl ether; dichloromethane; toluene;
1.1: Dess-Martin oxidation / 2.1: Grignard reaction / 3.1: Dess-Martin oxidation / 6.1: Dess-Martin oxidation / 9.1: Mitsunobu reaction;
DOI:10.1016/j.tetlet.2011.03.154