Iopamidol

Base Information Edit

Chemical Name:Iopamidol
CAS No.:60166-93-0
Molecular Formula:C17H22I3N3O8
Molecular Weight:777.09
Hs Code.:2924296000
European Community (EC) Number:262-093-6
NSC Number:759636
UNII:JR13W81H44
DSSTox Substance ID:DTXSID1023158
Nikkaji Number:J18.254K
Wikipedia:Iopamidol
Wikidata:Q424788
NCI Thesaurus Code:C47567
RXCUI:5966
Metabolomics Workbench ID:54439
ChEMBL ID:CHEMBL1200932
Mol file:60166-93-0.mol

Synonyms:B 15,000;B 15000;B-15,000;B-15000;B15,000;B15000;Gastromiro;Iopamidol;Iopamidol, (+-)-Isomer;Iopamidol, (R)-Isomer;Iopamidol, Sodium Salt, (S)-Isomer;Iopamiro;Isovue;Isovue 370;Jopamidol;Niopam;Solutrast;Solutrast 370;Solutrast Gastro;SQ 13,396

Suppliers and Price of Iopamidol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Iopamidol
2mg
$ 60.00

Sigma-Aldrich
Iopamidol
200mg
$ 366.00

Sigma-Aldrich
Iopamidol European Pharmacopoeia (EP) Reference Standard
i0329000
$ 190.00

Sigma-Aldrich
Iopamidol Pharmaceutical Secondary Standard; Certified Reference Material
500mg
$ 166.00

DC Chemicals
Iopamidol >98%
1 g
$ 800.00

Crysdot
Iopamidol 98+%
100mg
$ 102.00

AvaChem
Iopamidol
100mg
$ 119.00

AvaChem
Iopamidol
25mg
$ 59.00

American Custom Chemicals Corporation
IOPAMIDOL 95.00%
1MG
$ 152.25

American Custom Chemicals Corporation
IOPAMIDOL 95.00%
10MG
$ 704.55

Total 115 raw suppliers

Chemical Property of Iopamidol Edit

Chemical Property:

Appearance/Colour:White Crystalline Powder
Melting Point:>320 °C (dec)
Boiling Point:785.3 °C at 760 mmHg
PKA:pKa (25°) 10.70
Flash Point:428.8 °C
PSA：188.45000
Density:2.281 g/cm³
LogP:-0.15950
Storage Temp.:-20?C Freezer
Solubility.:Freely soluble in water, very slightly soluble in methanol, practically insoluble in ethanol (96 per cent) and in methylene chloride
Water Solubility.:473.7g/L(25 oC)
XLogP3:-2.4
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:10
Exact Mass:776.8541
Heavy Atom Count:31
Complexity:583

Purity/Quality:

99.9% ^*data from raw suppliers

Iopamidol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC(C(=O)NC1=C(C(=C(C(=C1I)C(=O)NC(CO)CO)I)C(=O)NC(CO)CO)I)O
Isomeric SMILES:C[C@@H](C(=O)NC1=C(C(=C(C(=C1I)C(=O)NC(CO)CO)I)C(=O)NC(CO)CO)I)O
Recent ClinicalTrials:Advanced MRI Scan Before and After Radiation Therapy for the Detection of Intracranial Metastasis
Recent EU Clinical Trials:Evaluation of the risk of nephrotoxicity caused by the intravenous administration of nonionic iodinated contrast media
Recent NIPH Clinical Trials:Investigation of safety when using hypoosmotic nonionic iodinated contrast agent in videofluoroscopic examination of swallowing
Uses Iopamidol is an organic iodine compound and used as a nonionic radiocontrast medium. Diagnostic aid (radiopaque medium). Iopamidol blocks x-rays as they pass through the body, thereby allowing body structures not containing iodine to be visualized. The degree of opacity produced by iopamidol is directly proportional to the total amount of the iodinated contrast agent in the path of the x-rays. The visualization of body structures is dependent upon the distribution and elimination of iopamidol. (NCI05)
Therapeutic Function Diagnostic aid (radiopaque medium)

Technology Process of Iopamidol

There total 20 articles about Iopamidol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%