4-(dodecylsulfanyl)-4-oxobutanoic acid

Base Information

• Chemical Name: 4-(dodecylsulfanyl)-4-oxobutanoic acid
• CAS No.: 88449-82-5
• Molecular Formula: C₁₆H₃₀O₃S
• Molecular Weight: 302.478
• Mol file: 88449-82-5.mol

Synonyms:Succinicacid, thiol-, S-dodecyl ester (5CI); NSC 520478

Chemical Property of 4-(dodecylsulfanyl)-4-oxobutanoic acid

Chemical Property:

• Vapor Pressure: 1.65E-08mmHg at 25°C
• Boiling Point: 427.6°Cat760mmHg
• Flash Point: 212.4°C
• Density: 1.013g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(dodecylsulfanyl)-4-oxobutanoic acid

There total 2 articles about 4-(dodecylsulfanyl)-4-oxobutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

succinic acid anhydride (108-30-5) + 1-dodecylthiol (112-55-0) → thiosuccinic acid S-dodecyl ester (88449-82-5)

Guidance literature:

With pyridine; at 20 - 40 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.tetlet.2020.152242

Reference yield:

1-dodecylbromide (143-15-7) → thiosuccinic acid S-dodecyl ester (88449-82-5)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / Versetzen mit 1.5 Mol 30prozentiger NaOH und weiteres 2-stdg.Kochen

2: pyridine

With pyridine; ethanol;

DOI:10.1002/pol.1948.120030108

upstream raw materials:

succinic acid anhydride

1-dodecylthiol

1-dodecylbromide

Refernces