4-CHLOROBENZENESULFONIC ACID SODIUM SALT

Base Information

• Chemical Name: 4-CHLOROBENZENESULFONIC ACID SODIUM SALT
• CAS No.: 5138-90-9
• Molecular Formula: C6H5 Cl O3 S . Na
• Molecular Weight: 214.605
• Hs Code.: 2904909090
• Mol file: 5138-90-9.mol

Synonyms:Benzenesulfonicacid, 4-chloro-, sodium salt (9CI); Benzenesulfonic acid, p-chloro-, sodiumsalt (6CI,7CI,8CI); Sodium 4-chlorobenzenesulfonate; Sodiump-chlorobenzenesulfonate; p-Chlorobenzenesulfonic acid sodium salt

Chemical Property of 4-CHLOROBENZENESULFONIC ACID SODIUM SALT

Chemical Property:

• Vapor Pressure: 0.00696mmHg at 25°C
• Boiling Point: 258.6°Cat760mmHg
• Flash Point: °C
• PSA: 65.58000
• Density: 1.551g/cm³
• LogP: 2.32490
• Water Solubility.: almost transparency

Purity/Quality:

98%,99%, ^*data from raw suppliers

Sodium 4-Chlorobenzenesulfonate >98.0%(HPLC)(T) ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 4-CHLOROBENZENESULFONIC ACID SODIUM SALT

There total 5 articles about 4-CHLOROBENZENESULFONIC ACID SODIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

C43H49ClNO14S(1-)*Na(1+) → sodium p-chlorobenzenesulphinate (14752-66-0) + sodium 4-chlorobenzenesulfonate (5138-90-9) + rifamycin S (13553-79-2)

Guidance literature:

In ethyl acetate; at 70 ℃; for 4h; Product distribution;

DOI:10.1246/bcsj.61.2425

Reference yield:

4-Chloro-benzenesulfonic acid toluene-4-sulfonylmethyl ester (31081-11-5) → formaldehyd (50-00-0,30525-89-4,61233-19-0) + sodium 4-chlorobenzenesulfonate (5138-90-9) + sodium 4-methylbenzenesulfinate (824-79-3)

Guidance literature:

With sodium hydroxide; cetyltrimethylammonim bromide; In water; at 32.1 ℃; Rate constant; Mechanism; solvolysis in H₂O-dioxane;

DOI:10.1021/jo00196a010

Reference yield:

sodium p-chlorobenzenesulphinate (14752-66-0) → sodium 4-chlorobenzenesulfonate (5138-90-9)

Guidance literature:

With oxygen; In various solvent(s); at 19 - 21 ℃; for 1h;

DOI:10.1246/bcsj.69.1391

upstream raw materials:

4-Chloro-benzenesulfonic acid toluene-4-sulfonylmethyl ester

α-(p-chlorobenzenesulfonyloxy)acetophenone

sodium 3,4-dichlorobenzenesulfonate

4-Chlor-1-benzolsulfonsaeure-trimethylsilylester

Downstream raw materials:

(E)-1-((2-bromo-2-phenylvinyl)sulfonyl)-4-chlorobenzene

(E)-1-chloro-4-(styrylsulfonyl)benzene

para-chlorobenzoic acid

4-hydroxymethylbiphenyl-4'-sulphonic acid

Refernces

• 1、 Niestroj, Michael,Lube, Andreas,Neumann, Wilhelm P.. "Synthesis of Aromatic and Olefinic Sodium Sulfonates by Electrophilic Destannylation with Trimethylsilyl Chlorosulfonate". . p. 575 - 580. Retrieved 2007/10/02.
• 2、 Yousaf, T. I.,Lewis, E. S.. "Enolate Structures Contributing to the Transition State for Nucleophilic Substitution on α-Substituted Carbonyl Compounds". . p. 6137 - 6142. Retrieved 2007/10/02.