Acetophenone phenylhydrazone

Base Information

• Chemical Name: Acetophenone phenylhydrazone
• CAS No.: 583-11-9
• Molecular Formula: C₁₄H₁₄N₂
• Molecular Weight: 210.279
• Hs Code.: 2928000090
• NSC Number: 68553
• Mol file: 583-11-9.mol

Synonyms:Acetophenone phenylhydrazone;583-11-9;N-[(E)-1-phenylethylideneamino]aniline;(2E)-1-phenyl-2-(1-phenylethylidene)hydrazine;(E)-1-PHENYL-2-(1-PHENYLETHYLIDENE)HYDRAZINE;59130-82-4;Acetophenone phenyl hydrazone;1-PHENYLETHANONE PHENYLHYDRAZONE;Ethanone, phenylhydrazone;Acetophenone, phenylhydrazone;SCHEMBL13345208;CPSCIFXVLXCFIQ-NTCAYCPXSA-N;NSC68553;NSC 68553;NSC-68553;STK160729;Ethanone, 1-phenyl-, phenylhydrazone;AKOS000313776;ethanone, 1-phenyl-, 2-phenylhydrazone

Chemical Property of Acetophenone phenylhydrazone

Chemical Property:

• Vapor Pressure: 0.000169mmHg at 25°C
• Boiling Point: 330.2°Cat760mmHg
• Flash Point: 153.5°C
• PSA: 24.39000
• Density: 1g/cm³
• LogP: 3.59570
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 210.115698455
• Heavy Atom Count: 16
• Complexity: 223

Purity/Quality:

99% ^*data from raw suppliers

1-PHENYLETHANONE PHENYLHYDRAZONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NNC1=CC=CC=C1)C2=CC=CC=C2
• Isomeric SMILES: C/C(=N\NC1=CC=CC=C1)/C2=CC=CC=C2

Technology Process of Acetophenone phenylhydrazone

There total 18 articles about Acetophenone phenylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

acetophenone (98-86-2) + phenylhydrazine (100-63-0) → N-(1-phenylethylidene)phenylhydrazine (583-11-9,59130-82-4)

Guidance literature:

With oxaline; In neat (no solvent); at 25 - 30 ℃; for 0.0666667h; Green chemistry;

DOI:10.1016/j.molliq.2013.11.036

Reference yield: 95.0%

phenylhydrazine hydrochloride (59-88-1) + acetophenone (98-86-2) → N-(1-phenylethylidene)phenylhydrazine (583-11-9,59130-82-4)

Guidance literature:

With sodium acetate; In ethanol; at 80 ℃; for 0.0833333h; Microwave irradiation; air-cooling;

DOI:10.1021/co100015b

Reference yield: 84.0%

1-Phenylethanol (98-85-1,13323-81-4) + phenylhydrazine (100-63-0) → N-(1-phenylethylidene)phenylhydrazine (583-11-9,59130-82-4)

Guidance literature:

1-Phenylethanol; With 3,6-bis(triphenylphosphonium)cyclohexene dichromate; at 20 ℃; for 0.0833333h;

phenylhydrazine; for 0.3h;

DOI:10.1080/10426500601015724

upstream raw materials:

sodium ethanolate

aniline

acetophenone-(2-phenyl semicarbazone)

phenylhydrazine hydrochloride

Downstream raw materials:

2-(benzo[d]thiazol-2-yl)-3-(1,3-diphenyl-1H-pyrazol-4-yl)acrylonitrile

2-(1H-benzo[d]imidazol-2-yl)-3-(1,3-diphenyl-1H-pyrazol-4-yl)acrylonitrile

4-(3-(4-(methylthio)phenyl)-1-phenyl-4,5-dihydro-1H-pyrazol-5-yl)-1,3-diphenyl-1H-pyrazole

4-(3-(2,4-dichlorophenyl)-1-phenyl-4,5-dihydro-1H-pyrazol-5-yl)-1,3-diphenyl-1H-pyrazole

Refernces

• 1、 -. "Novel carboxamide compound and compositions for preventing or treating metabolic diseases comprising the same". Paragraph 0095-0099; 0108-0109. . Retrieved 2021/09/14.
• 2、 Dalal, Sunita,Kumar, Gourav,Kumar, Ramesh,Kumar, Suresh,Kumari, Meena,Saroha, Bhavna. "Design, synthesis, biological evaluation, and molecular docking studies of some novel N,N-dimethylaminopropoxy-substituted aurones". . . Retrieved 2021/10/25.