Benzo[g]phthalazine

Base Information

• Chemical Name: Benzo[g]phthalazine
• CAS No.: 260-35-5
• Molecular Formula: C12H8 N2
• Molecular Weight: 180.209
• DSSTox Substance ID: DTXSID70511890
• Nikkaji Number: J3.075.078K
• Wikidata: Q82370904
• Mol file: 260-35-5.mol

Synonyms:Benzo[g]phthalazine;260-35-5;SCHEMBL8606886;DTXSID70511890

Chemical Property of Benzo[g]phthalazine

Chemical Property:

• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 180.068748264
• Heavy Atom Count: 14
• Complexity: 183

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C=C3C=NN=CC3=CC2=C1

Technology Process of Benzo[g]phthalazine

There total 1 articles about Benzo[g]phthalazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

2-naphthaldazine (2144-02-7) → naphthalene (91-20-3,71998-51-1,72931-45-4) + 1-(2-naphthyl)-benzo(g)-phthalazine (81452-40-6) + benzo[f]phthalazine (229-72-1) + benzo(g)phthalazine (260-35-5)

Guidance literature:

With PPA; at 230 - 240 ℃; for 1h; Yields of byproduct given;

DOI:10.1016/S0040-4039(01)92421-9

Reference yield: 89.0%

N-allyl-N-(prop-1-yn-1-yl)-4-methylbenzenesulfonamide (1239945-53-9) + benzo(g)phthalazine (260-35-5) → C25H23NO2S

Guidance literature:

With trifluoromethylsulfonic anhydride; In 1,2-dichloro-ethane; at 100 ℃; for 3h; Inert atmosphere; Sealed tube; Green chemistry;

DOI:10.1021/acs.orglett.8b02431

Reference yield: 84.0%

triisopropyl((phenylethynyl)oxy)silane (96845-72-6) + benzo(g)phthalazine (260-35-5) → triisopropyl(3-phenylanthracen-2-yloxy)silane (1379772-66-3)

Guidance literature:

With [2,2]bipyridinyl; silver(I) triflimide; In dichloromethane; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1021/ja302537j

upstream raw materials:

2-naphthaldazine

Downstream raw materials:

1,4-Diphenylbenzophthalazin

triisopropyl(3-phenylanthracen-2-yloxy)silane

Refernces