2-formylmethoxyhordenine

Base Information

• Chemical Name: 2-formylmethoxyhordenine
• CAS No.: 103847-05-8
• Molecular Formula: C₁₂H₁₇NO₂
• Molecular Weight: 207.272
• Mol file: 103847-05-8.mol

Synonyms:2-formylmethoxyhordenine

Chemical Property of 2-formylmethoxyhordenine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 2-formylmethoxyhordenine

There total 1 articles about 2-formylmethoxyhordenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methoxyphenethyl-dimethylamine (775-33-7) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 2-formylmethoxyhordenine (103847-05-8)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction; 1.) ether, RT, 30 h, 2.) 5 h;

DOI:10.1016/S0040-4020(01)97202-3

Reference yield: 81.0%

2-formylmethoxyhordenine (103847-05-8) + acetone (67-64-1) → 4-(2'-methoxyhordeninyl)-(E)-but-3-en-2-one (103847-08-1)

Guidance literature:

With sodium hydroxide; In water; Ambient temperature;

DOI:10.1016/S0040-4020(01)97202-3

Reference yield:

2-formylmethoxyhordenine (103847-05-8) → 1-(2'-methoxyhordeninyl)-3-methyl-1,3-butadiene (103847-09-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / NaOH / H₂O / Ambient temperature

2: 1.) BuLi / 1.) 0 deg C, THF, 30 min, 2.) -78 deg C, THF, 30 min

With sodium hydroxide; n-butyllithium; In water;

DOI:10.1016/S0040-4020(01)97202-3

upstream raw materials:

4-methoxyphenethyl-dimethylamine

N,N-dimethyl-formamide

Downstream raw materials:

4-(2'-methoxyhordeninyl)-(E)-but-3-en-2-one

1-(2'-methoxyhordeninyl)-3-methyl-1,3-butadiene

{2-[3-(6-{(E)-2-[5-(2-Dimethylamino-ethyl)-2-methoxy-phenyl]-vinyl}-3,6-dimethyl-cyclohex-2-enyl)-4-methoxy-phenyl]-ethyl}-dimethyl-amine

Refernces