Fenticlor

Base Information

• Chemical Name: Fenticlor
• CAS No.: 97-24-5
• Molecular Formula: C12H8Cl2O2S
• Molecular Weight: 287.166
• Hs Code.: 2930909090
• European Community (EC) Number: 202-568-7
• NSC Number: 55636,4112
• UNII: D61659OVD0
• DSSTox Substance ID: DTXSID4026137
• Nikkaji Number: J4.947F
• Wikipedia: Fenticlor
• Wikidata: Q5443595
• NCI Thesaurus Code: C65671
• Metabolomics Workbench ID: 67018
• ChEMBL ID: CHEMBL473535
• Mol file: 97-24-5.mol

Synonyms:fentichlor

Chemical Property of Fenticlor

Chemical Property:

• Appearance/Colour: white to pale yellow powder
• Vapor Pressure: 1.55E-07mmHg at 25°C
• Melting Point: 175 °C
• Refractive Index: 1.73
• Boiling Point: 416.688 °C at 760 mmHg
• PKA: 7.91±0.48(Predicted)
• Flash Point: 205.806 °C
• PSA: 65.76000
• Density: 1.588 g/cm³
• LogP: 4.55580
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 285.9622061
• Heavy Atom Count: 17
• Complexity: 231

Purity/Quality:

98% ^*data from raw suppliers

Bis(2-hydroxy-5-chlorophenyl) Sulfide ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Uses -> Biocides/Disinfectants
• Canonical SMILES: C1=CC(=C(C=C1Cl)SC2=C(C=CC(=C2)Cl)O)O
• Recent ClinicalTrials: A Pumpkin Seed, Isoflavonoid and Cranberry Mix in LUTS/BPH
• Uses: Fungicide; especially used against Monosporium apiospermum: Reifferscheid, Seeliger, Dtsch. Med. Wochenschr. 80, 1841, 1850 (1955). Fentichlor is a fungicide especially used against Monosporium apiospermum; topical antifungal and antibacterial agent in hairdressings, antifungal creams, and ointments; thermoplastic resin.
• Therapeutic Function: Antifungal

Technology Process of Fenticlor

There total 7 articles about Fenticlor which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

4-chloro-phenol (106-48-9,82344-39-6) → 4,4'-dichloro-2,2'-thiodiphenol (97-24-5)

Guidance literature:

With tetraethylammonium perchlorate; trichloroacetic acid; In dichloromethane; for 2h; Ambient temperature; working pot.: 2.2 V vs SCE;

Reference yield:

2,2'-sulfoxide-bis(4-chlorophenol) (29097-31-2) → 4,4'-dichloro-2,2'-thiodiphenol (97-24-5)

Guidance literature:

With hydrogenchloride; at 100 ℃; im Rohr;

Reference yield:

2,2'-dihydroxyldiphenyl sulfide (13693-59-9) → 4,4'-dichloro-2,2'-thiodiphenol (97-24-5)

Guidance literature:

With sulfuryl dichloride; 1,2-dichloro-benzene;

upstream raw materials:

2,2'-dihydroxyldiphenyl sulfide

2,2'-sulfoxide-bis(4-chlorophenol)

4-chloro-phenol

carbon disulfide

Downstream raw materials:

bis-(5-chloro-2-hydroxy-3-piperidinomethyl-phenyl)-sulfide

4,4'-dichloro-6,6'-bis-morpholinomethyl-2,2'-sulfanediyl-di-phenol

4,4'-dichloro-6,6'-bis-dimethylaminomethyl-2,2'-sulfanediyl-di-phenol

2,10-dichloro-6-(4'-methylphenoxy)-4,8-dinitrodibenzo[d,g][1,3,6,2]dioxathiaphosphocin-6-oxide

Refernces

• 1、 Elothmani, Driss,Do, Quang Tho,Simonet, Jacques,Guillanton, Georges Le. "Utilisations synthetiques d'une electrode soluble au soufre. III. Creation de l'enchainement C-S-C a partir d'ethers aromatiques et de phenols". . p. 779 - 788. Retrieved 2007/10/02.
• 2、 -. "Carbonates of acetylenic alcohols". . . Retrieved 2008/06/13.