N-formylnorleucine phenyl ester

Base Information

• Chemical Name: N-formylnorleucine phenyl ester
• CAS No.: 222845-16-1
• Molecular Formula: C₁₃H₁₇NO₃
• Molecular Weight: 235.283
• Mol file: 222845-16-1.mol

Synonyms:N-formylnorleucine phenyl ester

Chemical Property of N-formylnorleucine phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-formylnorleucine phenyl ester

There total 2 articles about N-formylnorleucine phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-hexanoic acid (616-06-8) → N-formylnorleucine phenyl ester (222845-16-1)

Guidance literature:

Multi-step reaction with 2 steps

1: Ac₂O / 3 h / Ambient temperature

2: Et₃N, 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate / CH₂Cl₂ / 3 h / Ambient temperature

With acetic anhydride; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; In dichloromethane;

DOI:10.1021/ja983017e

Reference yield:

2-formamidohexanoic acid (118659-59-9) + phenol (108-95-2,27073-41-2) → N-formylnorleucine phenyl ester (222845-16-1)

Guidance literature:

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; In dichloromethane; for 3h; Yield given; Ambient temperature;

DOI:10.1021/ja983017e

Reference yield:

N-formylnorleucine phenyl ester (222845-16-1) → 2-formamidohexanoic acid (118659-59-9) + phenol (108-95-2,27073-41-2)

Guidance literature:

With 17E₈ antibody; water; at 24.5 ℃; Rate constant;

DOI:10.1021/ja9605329

upstream raw materials:

2-formamidohexanoic acid

phenol

2-amino-hexanoic acid

Downstream raw materials:

2-formamidohexanoic acid

phenol

Refernces