2,6-Dihydroxypyridine

Base Information

• Chemical Name: 2,6-Dihydroxypyridine
• CAS No.: 626-06-2
• Molecular Formula: C5H5NO2
• Molecular Weight: 111.1
• Hs Code.: 2933399090
• European Community (EC) Number: 210-927-4
• UNII: 54009B6TXP
• DSSTox Substance ID: DTXSID90211643
• Nikkaji Number: J58.008B
• Wikipedia: 2,6-Dihydroxypyridine
• Wikidata: Q4596805
• Metabolomics Workbench ID: 49867
• ChEMBL ID: CHEMBL3086507
• Mol file: 626-06-2.mol

Synonyms:2,6-DHP;2,6-dihydroxy-pyridine;2,6-dihydroxypyridine;2,6-dihydroxypyridine hydrochloride;2,6-dihydroxypyridine sulfate

Chemical Property of 2,6-Dihydroxypyridine

Chemical Property:

• Melting Point: 202-203 °C
• Boiling Point: 387.2 °C at 760 mmHg
• PKA: 4.50±0.10(Predicted)
• Flash Point: 188 °C
• PSA: 53.35000
• Density: 1.379 g/cm³
• LogP: 0.49280
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 111.032028402
• Heavy Atom Count: 8
• Complexity: 169

Purity/Quality:

99%, ^*data from raw suppliers

2,6-Dihydroxypyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=O)NC(=C1)O

Technology Process of 2,6-Dihydroxypyridine

There total 11 articles about 2,6-Dihydroxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

→ 2,6-dihydroxypyridine (626-06-2)

Guidance literature:

Reference yield:

2,6-dimethoxypyridine (6231-18-1,122797-02-8) → 2,6-dihydroxypyridine (626-06-2)

Guidance literature:

With hydrogenchloride; sodium hydroxide; acetic acid; In water; ethyl acetate;

Reference yield:

2.6-diaminopyridine (141-86-6) → 2,6-dihydroxypyridine (626-06-2)

Guidance literature:

With sulfuric acid; at 155 ℃; Erwaermen des Reaktionsprodukts in neutralisierter wss.Loesung;

upstream raw materials:

2.6-diaminopyridine

2,6-bis(ethoxy)pyridine

2,6-dihydroxy-pyridine-3,5-dicarboxylic acid diethyl ester

sulfuric acid

Downstream raw materials:

2,2'-<2,6-pyridinediylbis(oxy-2,1-ethanediyloxy)>diphenyl dibenzyl ether

3,4,4',5'-tetramethylazapsoralen

3,4,4'-trimethyl-8-azapsoralen

3,4-dimethyl-7-(2'-oxocyclohexyloxy)pyrano<2,3-b>pyridin-2-one

Refernces

• 1、 -. "Water soluble cationic azo dyestuffs containing a cyclammonium group". . . Retrieved 2008/06/13.